M1 blood storage Flashcards

1
Q

Recommended sodium phosphate.

A

BRAXTON HICKS (1868)

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2
Q

Performed direct transfusion.

A

ALEXIS CARREL (1908)

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3
Q

Sodium Citrate was used as an anticoagulant solution for transfusions.

A

HUSTIN (1914)

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4
Q

What anticoagulant did Hustin (1914) discovered?

A

Sodium Citrate

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5
Q

What anticoagulant did Braxton Hicks (1868) discovered?

A

Sodium Phosphate

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6
Q

Determined the minimum amount of sodium citrate needed for anticoagulation and demonstrated its nontoxicity.

A

LEWISOHN (1915)

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7
Q

Introduced a citrate-dextrose solution for the preservation of blood.

A

ROUS & TURNER (1916)

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8
Q

What used for blood preservation with glucose.

A

Acid-Citrate-Dextrose (ACD)

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9
Q

It helps preserve the viability of blood because it serves as an additional source of nutrients for the cell.

A

Glucose

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10
Q

The year of the first blood bank was established in a Leningrad hospital

A

1932

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11
Q

He established the first hospital blood bank in the United States.

A

BERNARD FANTUS (1937)

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12
Q

Discovered the Rh blood group system

A

LANDSTEINER, WEINER, LEVINE AND STETSON (1939-1940)

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13
Q

He pioneered the works of blood preservation research during the war.

A

Dr. Charles Drew

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14
Q

Appointed director of the 1st American Red Cross Blood Bank at Presbyterian Hospital

A

DR. CHARLES DREW (FEBRUARY 1941)

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15
Q

Introduced the formula for the preservative Acid-Citrate Dextrose (ACD) to be used instead of sodium citrate.

A

LOUTIT AND MOLLISON OF ENGLAND (1943)

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16
Q

AUDREY SMITH (1950)

A

Reported the use of glycerol cryoprotectant for freezing red blood cells

17
Q

RBC freezing can help store rare blood line up to 10 years

A

Glycerol Cryoprotectant

18
Q

Introduced an improved preservative solution, Citrate-Phosphate-Dextrose (CPD) which was less acidic and eventually replaced Acid-Citrate Dextrose (ACD) as the standard preservative used for storage of blood/red cells in liquid form.

A

GIBSON (1957)

19
Q

The use of “Phosphate” is what made CPD less acidic than ACD.

A

GIBSON (1957)

20
Q

Shelf-life of blood stored in CPD

A

2 - 4 ºC was 21 days

21
Q

CPDA-1 extends the shelf life of whole blood from 28- 35 days, increasing the blood supply and facilitating resource sharing among blood banks.

A

1979

22
Q

The addition of adenine improved the synthesis of ATP in the stored blood, which prolonged the storage of blood/red cells

A

2 - 4 ºC to 35 days

23
Q

refers to the 120 days span of RBCs within the body

A

Lifespan

24
Q

refers to the lifespan of RBCs during the storage period.

A

Shelf life