Lytes Flashcards

1
Q

How is TBW calculated?

A

as Kg x 0.6 = Liters total body water

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2
Q

How much of total body water is intracellular?

A

2/3rds

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3
Q

How much of extracellular body water is intravascular?

A

25%

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4
Q

How is total body water distributed?

A
  • 2/3rds intracellular
  • 1/3rd extracellular
    • 25% intravascular
    • 75% interstitial
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5
Q

What is the blood volume of an average adult? average child?

A
  • 70kg male has 5L blood volume
  • children have 80cc/kg blood volume
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6
Q

What is the makeup of LR?

A
  • 130 mEq sodium
  • 4 mEq potassium
  • 2.7 mEq calcium
  • 109 mEq chloride
  • 28 mEq bicarb
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7
Q

How much sodium and potassium does a person need each day?

A
  • 0.5 - 1.0 mEq of potassium
  • 1.0 - 2.0 mEq of sodium
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8
Q

How many calories are in a liter of D5?

A
  • D5 = 50g of dextrose
  • dextrose has 3.4kcal/g
  • total = 170 kcal
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9
Q

How is serum osmolality calculated?

A
  • Osm = 2 x Na + glucose/18 + BUN/2.8
  • simplifies to 2 x Na + 10
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10
Q

How can you differentiate SIADH from excess free water?

A
  • calculate serum osmolality (2 x Na + 10) and compare it to urine osmolality
  • if urine osmolality is lower than likely excess free water
  • if urine osmolality is higher than likely SIADH
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11
Q

How is SIADH treated?

A
  • fluid restriction
  • normal saline
  • vaptans (vasopressin antagonists)
  • demeclocycline
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12
Q

What are the two most likely causes of hypernatremia?

A

dehydration and diabetes insipidus

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13
Q

How is free water deficit calculated?

A

(actual Na - desired Na)/desired Na x kg x 0.6

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14
Q

What are the symptoms of hypocalcemia?

A
  • weakness
  • perioral tingling
  • Chovstek’s sign (tap on facial nerve and get a perioral twitch)
  • Trousseau’s sign (carpal pedal spasm with blood pressure cuff)
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15
Q

How is calcium corrected for albumin?

A
  • normal albumin = 4
  • add 0.8 to calcium for every 1 albumin is below 4
  • e.g. if albumin is 2, add 1.6 to calcium
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16
Q

What are the two most common causes of hypercalcemia?

A
  • in an outpatient: hyperparathryoidism
  • in an inpatient: malignancy
17
Q

What are the symptoms of hypercalcemia?

A

stones, bones, groans, and psychiatric overtones

18
Q

How is hypercalcemia treated?

A
  • crystalloid resuscitation
  • loop diuretics
  • biphosphonates
  • calcitonin
  • glucocorticoids
  • dialysis
19
Q

How much should PaCO2 affect pH?

A
  • change in pH = 0.8 x change in CO2
  • .1 change in pH for every 12 change in CO2
20
Q

How is anion gap calculated?

A

Na + K - Cl - HCO3, normal is < 12

21
Q

What are the possible explanations for a gap acidosis (> 12)?

A
  • M: methanol
  • U: uremia
  • D: DKA
  • P: paracetamol/paraldehyde
  • I: isoniazid/iron
  • L: lactate
  • E: ethanol, ethylene glycol
  • S: salicylates
22
Q

What are the possible causes of a non-gap metabolic acidosis (< 12)?

A
  • diarrhea
  • RTA
  • fistulas
  • hyperchloremia
  • acetazolamide
23
Q

What is the primary intracellular cation?

A

potassium

24
Q

What is the effect of lasix on potassium?

A

potassium wasting

25
Q

What metabolic derangements are expected for a baby with pyloric stenosis?

A

hypochloremic, hypokalemic

26
Q

How does acidosis affect the oxygen dissociation curve?

A

it shifts the curve to the right so that oxygen unloads easier

27
Q

High NGT output or vomiting leads to which electrolyte abnormalities?

A

hypochloremic and metabolic alkalosis

28
Q

Diarrhea leads to which electrolyte abnormalities?

A

hypokalemic metabolic acidosis

29
Q

What will the gas look like for a mountain climber?

A

respiratory alkalosis