Colorectal Flashcards

1
Q

What are the two major collaterals between the SMA and IMA?

A
  • the marginal artery
  • the arc of Riolan
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2
Q

What are the watershed areas of the colon?

A

the splenic flexure and the transition zone between superior and middle rectum

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3
Q

What is the blood supply to the rectum?

A
  • superior rectal artery off the IMA
  • middle off the internal iliac
  • inferior off the pudendal
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4
Q

What is the venous drainage of the rectum?

A
  • superior to the IMA and portal circulation
  • middle and inferior to the internal iliac and systemic circulation
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5
Q

What defines the anal canal?

A
  • proximal: puborectalis sling
  • distal: anal verge
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6
Q

What defines the anal margin?

A

within 5cm of the anal verge

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7
Q

How are anal fissures treated?

A
  • start with fiber, sit baths, and topical anesthetics
  • can advance to topical nitrates and CCBs
  • consider botox, LIS, or anocutaneous flap
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8
Q

What are contraindications to lateral internal sphincterotomy for anal fissure?

A
  • fecal incontinence
  • women of childbearing age
  • prior obstetrical injuries
  • IBD
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9
Q

Describe the course of most anorectal fistulas.

A
  • anteriorly they tend to be linear unless > 3cm from the anal verge
  • posteriorly then tend to be curvelinear
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10
Q

When are antibiotics indicated for those with anorectal abscesses?

A

when there is cellulitis, systemic signs of infection, or they are immunocompromised

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11
Q

What proportion of patients with anorectal abscesses develop fistulas?

A

about one third

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12
Q

What is the difference between a high and low trans-sphincteric anorectal fistula?

A
  • high involve > 33% of the sphincter complex
  • low involve less
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13
Q

What is the goal of a fistula?

A

to convert a high fistula to a low one, thereby preparing the tract for later intervention

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14
Q

How are internal hemorrhoids classified?

A
  • I: internal only
  • II: spontaneously reduce
  • III: manually reduce
  • IV: don’t reduce
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15
Q

How should thrombosed hemorrhoids be managed?

A
  • can do a thrombectomy if < 72hrs after onset
  • otherwise manage expectantly with symptomatic control
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16
Q

When should patients with diverticulitis have a colonoscopy?

A

6 weeks after resolution of their episode

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17
Q

Describe the natural course of diverticulitis.

A

the first episode tends to be the worst

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18
Q

Who should have a sigmoidectomy for diverticulitis?

A
  • anyone with complicated disease needs an operation at some point
  • those with uncomplicated disease get a more customized approach with shared decision making since the first episode tends to be the worst
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19
Q

What is the surgery of choice for someone with complicated C. diff?

A

subtotal colectomy with ileostomy

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20
Q

Sigmoid volvulus is discovered on AXR, what are the next steps?

A
  • CT scan to evaluate colonic viability
  • endoscopic decompression
  • sigmoidectomy during index admission
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21
Q

What are the risk factors for colonic perforation?

A
  • cecum > 12 cm
  • duration of Ogilvie’s > 6 days
22
Q

What medication is used to treat Ogilvie’s and what is the predominant side effect to know?

A
  • can use neostigmine (anti-acetylcholinesterase)
  • causes bradycardia
23
Q

What is the key component to a trans-abdominal rectal prolapse repair?

A

rectopexy, can add LAR or sigmoidectomy if patient has constipation

24
Q

What is the difference between a Delorme and Altemeier procedure?

A
  • Delorme: mucousectomy via perineal approach with muscle plication
  • Altemeier: full thickness rectosigmoidectomy via perineal approach with coloanal anastomosis
25
What is the main nutrient for colonocytes?
short chain fatty acids
26
What is the main nutrient for enterocytes?
glutamine
27
Which extra-colonic manifestations of UC typically improve with colectomy?
- arthropathy, erythema nodosum, and episcleritis - hepatic issues (PSC) do not
28
What are the colonoscopy recommendations for those with UC?
- start 8 years after diagnosis - perform every 1-2 years - taking random biopsies at 10cm intervals
29
When is malignancy an indication for colectomy in those with UC?
- multifocal invisible low grade dysplasia - invisible high grade dysplasia - frank malignancy
30
If patients with UC have an uninvolved rectum and get an ileorectal anastomosis, what are the screening recommendations?
annual endoscopy
31
What are Finney and Michelassi stricturopalsties?
- Finney: fold structured segment and make a common channel in the loop - Michelassi: side-to-side is-peristaltic stricturoplasty
32
What are the colon cancer screening recommendations for FAP?
start at 10-12 and perform annual sigmoidoscopies
33
What are the colon cancer screening recommendations for Lynch syndrome?
- start at 20-25 or ten years before the youngest family member - perform colonoscopies every 1-2 years
34
When should a surveillance colonoscopy be performed for the following: - 1 to 2 tubular adenomas - 3 adenomas - advanced adenomas (>1 cm, high grade dysplasia, villous histology) - hyperpalstic polyps
- 1 to 2 tubular adenomas: in 5 years - 3 adenomas: in 3 years - advanced adenomas (>1 cm, high grade dysplasia, villous histology): in 3 years - hyperpalstic polyps: in 10 years
35
Which colon cancers can be managed endoscopically?
those that can: - be removed in one piece - with negative margins - that are well-to-moderately differentiated - without lymphovascluar involvement - that are limited to the submucosa
36
How is colon cancer staged?
- T1: invades submucosa - T2: invades muscularis propria (stage I) - T3: invades pericolonic tissue - T4: invades serosa or surrounding structures (stage II) - N1: 1-3 nodes - N2: 4+ nodes (stage III)
37
What should be the distal margin on colon cancer resection?
5-7 cm to ensure adequate lymphadenectomy (need 12)
38
How many lymph nodes should be taken during colon resection for cancer?
at least 12
39
Which metastatic colon cancers can be resected?
those with limited hepatic or pulmonary mets
40
Which colon cancer patients get adjuvant therapy?
stage III and above (any nodal involvement)
41
What is FOLFOX?
- leucovorin (folinic acid) - fluorouracil - oxaliplatin
42
What is the most important prognostic factor when staging a rectal cancer?
identify the total distance between tumor and mesolectal fascia (the CRM, circumferential margin)
43
Who gets neoadjuvant chemoradiation for colon cancer? Adjuvant therapy?
- neoadjuvant for those with T3 or greater disease or any nodal disease - adjuvant for anyone with nodal disease who did not receive neoadjuvant therapy (anyone understaged) or anyone high stage II or greater who received neoadjuvant therapy
44
What are the histologic variants for anal squamous cell carcinoma?
- cloacogenic - basaloid - epidermoid - mucoepidermoid
45
What HPV serotypes are associated with anal SCC?
16 and 18
46
What is the nigro protocol?
- chemoradiation protocol as a first line treatment for anal SCC rather than APR - consists of 5-FU, mitomycin C, and radiation - followed by salvage APR if needed
47
How do you treat SCC of the anal margin?
like skin cancer with wide local excision
48
How is anal melanoma treated?
with APR
49
How is pouchitis treated in those with IPAA?
antibiotics, supportive care, and budesonide enemas if unresponsive
50
What should you suspect in a UC patient who develops chronic pouchitis?
misdiagnosis, actually have Crohn's
51
During a laparoscopy for possible appendicitis, it appears normal and the TI is inflamed. What is the diagnosis and next steps?
- likely Crohn's - if the cecum is uninvolved, still do the app but if it is involved, leave the appendix in place