lynelle stuff

Question 1

FAP gene

Answer 1

APC

Question 2

Lynch syndrome gene

Answer 2

DNA mismatch repair

Question 3

Lynch syndrome colon cancer location

Answer 3

Right side

Question 4

Oldest age for routine colon cancer screen

Answer 4

75

Question 5

UC vs crohn’s, who gets cancer more

Answer 5

UC

need colonoscopy 8 years after ddx

Question 6

tenesmus

Answer 6

feeling of not emptying bowel

Question 7

stool in right side colon

Answer 7

stool is semi- liquid

Question 8

Biologic actions of TNF include

Answer 8

PMN activation and degranulation
↑ vascular permeability
promotion of interleukins 1, 2, and 6;

numerous protective and adverse effects in sepsis.

Question 9

Rectal cancer mets to?

Answer 9

lungs- does not have portal drainage

higher than rectum–> liver

Question 10

The purpose of a cross-match is to determine ?

Answer 10

whether the recipient has circulating antibodies against donor HLA antigens

Question 11

Chronic rejection of liver transplant

Answer 11

• late complication- months - years later
• paucity of bile ducts due to immune mediated injury to the biliary epithelium
• “vanishing bile duct syndrome.”
• rx: transplant

Question 12

pre op imaging for colon cancer

Answer 12

ct ab/pelvis

need to know about mets before going in

Question 13

Charcot triad

Answer 13

suggests charcot’s triad:
right upper quadrant pain
jaundice
fever

Question 14

local infiltrate rectal cancers need?

Answer 14

neo-adjuvant radiation and chemo

Question 15

Radiation to mid abdomen is not good because?

Answer 15

Small bowel strictures

radiation does not play nice with hollow organs

Question 16

proper amount of nodes for proper colon ca resection

Answer 16

12

Question 17

what layer in bowel when invaded gets automatic chemo

Answer 17

serosa

T3 stage

Question 18

dissection name in rectal cancer that means you got all lymph nodes

Answer 18

TME

total meso-rectal resection

Question 19

Two cancer polyps in very different parts of bowel

Treatment?

Answer 19

total proctocolectomy (no more colon)

Question 20

Hartman’s procedure

Answer 20

end colostomy

takes away the sigmoid mostly

Question 21

Lymph node contrast types

Answer 21

IV contrast is really the only that will show it

Question 22

Stage of any perforated colon cancer

Answer 22

always t4

Question 23

Invades sub-mucosa

Answer 23

T1- microvascular invasion

needs true cancer surgery

Question 24

Invades muscularis

Answer 24

t2

Question 25

tumor lysis syndrome

Answer 25

• Mediated by cytotoxic T cells
• Hyperkalemia and hyperphosphatemia- lysis
• Hypocalcemia -result of precipitation of phosphate + calcium

Question 26

choledocofistuala rx

Answer 26

take down fistula