Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

internal 4th > lymphomas > Flashcards

lymphomas Flashcards

1
Q

2 types of cells in hodgkin

A

hodgkin cells
reed sternberg cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what classification do we use for lymphomas

A

anne harbour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

which cancer is extranodal involvement more common

A

NON HODGKIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

GOLD STANDARD FOR HODGKIN and why

A

CT SCAN - allows you to see the LN that you cannot easily palpate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what x ray findings can you see in hodgkin

A

‘bulky mediastinum ‘ you may be able to see where ist wider than 10 cm across

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

tx regimen for hodgkin

A
  1. chemo therapy
  2. radiothapry
  3. monoclonal ab- brentuximab
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

brentuximab

A

used for rhodgkin against CD30

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

DEFINTIVE TX HODGKIN

A

autologous stem cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are the chemo regimens for hodgkin

A

ABCD

BEA- COPP

STANDFORD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is th usual standard treatment regiment for hodgkin

A

ABVD+ RT (depending on how many areas are affected)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what happens in a refactory/relapsed case of hodgkin

A

go straight for the monoclonal ab’s like brentuximan - cd30 /nivolimab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what does stage 4 represent of hodgkin

A

extra nodal involvement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

prognostic factors of hodgkin

A

male
>45
anemia
hypoalbumimia
leukocytosis
stage 4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

classification of hodgkin

A

NS- most common
mixed cellularity
lymphocyte rich
lymphocyte depleted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

most common form of hodgkin

A

NS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

where are the most common sites for hodgkin lymphma

A

well since NS is the most common, then it’s usually more localised in the cervical and mediatinal LN/supraclavicula

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

LAB TESTS HODGKIN

A

anemia - normocytic
eosinphlia, neutrophilia
esr ,
LFTS
invcreased LDH
HYPERCALCEMIA- paraneoplastic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

name of the fever in hodgskin

A

pel ebstein fever - gradually increase then decline cyclically over a period of 1/2 weeks

19
Q

which lymphoma is better to have

A

HODGKIN

20
Q

WHICH LYMPHOMA IS MORE COMMON

A

NON HODG

21
Q

Which specific type of cell is more common in NON hodgkin

A

85 % are B cells
15%T cells

22
Q

eosinophilia and link to cancer

A

blood cancers

23
Q

rf for hodgkin lymphoma

A

HIV
immunosuppression
previous infection with EBV infectious mono

having automimme disease

im

24
Q

alcohol induced pain

A

refelctive of hodgkin

25
Q

symptoms of hodgkin

A

hepatosplenomehaly
lymphadenopathy
b symptoms
general cancer symptomsm

26
Q

diagnosis

A

lymph node bipsy to look for reed stenberg inside

26
Q

diagnosis

A

lymph node bipsy to look for reed stenberg inside

27
Q

epidemiology of hodgkin

A

bi modal

28
Q

stage 3 b anne harbour

A

both sides of diaphragm and more than 1 lymph nodes group affected
with b symptoms

29
Q

risk factor non H

A

NB- viral infections llike h.pylori, ebv, human lymtphotrophic virus

hiv
immunodeficiney
autoimmune - sjogren and celiac

30
Q

risk factor non H

A

NB- viral infections llike h.pylori, ebv, human lymtphotrophic virus

hiv
immunodeficiney
autoimmune - sjogren and celiac

31
Q

which lymphoma are more common B SYMPTOMS

A

NON HODGKUIN

32
Q

WHCIH LN IN NON HODGKIN

A

CERVICAL
AXIALLARY
INGUINAL

33
Q

WHCIH LN IN NON HODGKIN

A

CERVICAL
AXIALLARY
INGUINAL

34
Q

most common sites of extranodal disease in NON HODg

A

the gut
skin

35
Q

diagnois of non h

A

nuclleated rbc
high ldh
left shift
bm biopsy
LN bipsy

36
Q

what does left shift mean

A

immature wbc

37
Q

how do we calssify non hodgkin

A

high grade
low grade

38
Q

what is more favourable low grade or high grade non hodgkin

A

high grade because although aggressive tends to be easier to treat

38
Q

what is more favourable low grade or high grade non hodgkin

A

high grade because although aggressive tends to be easier to treat

39
Q

tx for non hodgkin

A

same as hodg chemo + rt

40
Q

what is actually affected in non hodgkin lymphoma

A

the LN
other sites of lymphatic tissue like skin, git,spleen (malt0
bm, blood

41
Q

R - CHOP

A

used to treat b cell non hodgkin lymphoma

internal 4th (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions