lymphomas Flashcards
2 types of cells in hodgkin
hodgkin cells
reed sternberg cells
what classification do we use for lymphomas
anne harbour
which cancer is extranodal involvement more common
NON HODGKIN
GOLD STANDARD FOR HODGKIN and why
CT SCAN - allows you to see the LN that you cannot easily palpate
what x ray findings can you see in hodgkin
‘bulky mediastinum ‘ you may be able to see where ist wider than 10 cm across
tx regimen for hodgkin
- chemo therapy
- radiothapry
- monoclonal ab- brentuximab
brentuximab
used for rhodgkin against CD30
DEFINTIVE TX HODGKIN
autologous stem cell
what are the chemo regimens for hodgkin
ABCD
BEA- COPP
STANDFORD
what is th usual standard treatment regiment for hodgkin
ABVD+ RT (depending on how many areas are affected)
what happens in a refactory/relapsed case of hodgkin
go straight for the monoclonal ab’s like brentuximan - cd30 /nivolimab
what does stage 4 represent of hodgkin
extra nodal involvement
prognostic factors of hodgkin
male
>45
anemia
hypoalbumimia
leukocytosis
stage 4
classification of hodgkin
NS- most common
mixed cellularity
lymphocyte rich
lymphocyte depleted
most common form of hodgkin
NS
where are the most common sites for hodgkin lymphma
well since NS is the most common, then it’s usually more localised in the cervical and mediatinal LN/supraclavicula
LAB TESTS HODGKIN
anemia - normocytic
eosinphlia, neutrophilia
esr ,
LFTS
invcreased LDH
HYPERCALCEMIA- paraneoplastic syndrome
name of the fever in hodgskin
pel ebstein fever - gradually increase then decline cyclically over a period of 1/2 weeks
which lymphoma is better to have
HODGKIN
WHICH LYMPHOMA IS MORE COMMON
NON HODG
Which specific type of cell is more common in NON hodgkin
85 % are B cells
15%T cells
eosinophilia and link to cancer
blood cancers
rf for hodgkin lymphoma
HIV
immunosuppression
previous infection with EBV infectious mono
having automimme disease
im
alcohol induced pain
refelctive of hodgkin
