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Medical Oncology Boards > Lymphoma > Flashcards

Lymphoma Flashcards

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USMLE® Step 1 flashcards
1
Q

Nodular lymphocyte predominant HL pathologic appearance and immunophenotyp[

A

popcorn appearance, CD15-, CD30-. CD45+

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2
Q

Classical HL immunophenotype

A

CD15+, CD30+

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3
Q

Stage I/II vs stage III/IV HL

A

one side or both side of diaphragm

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4
Q

Brentuximab vedotin AEs

A

peripheral neuropathy and potentiating bleomycin pulmonary toxicity

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5
Q

Treatment after 1st relapse cHL

A

ICE followed by autoSCT

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6
Q

Treatment of cHL relapsed after auto-SCT

A

brentuximab vedotin then alloSCT

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7
Q

HCV related lymphoma

A

splenic marginal zone lymphoma

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8
Q

Mantle cell lymphoma cytogenetics

A

t(11;14)

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9
Q

Follicular lymphoma cytogenetics

A

t(14;18)

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10
Q

Marginal zone lymphoma cytogenetics

A

t(11;18)

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11
Q

Lymphoplasmacytic lymphoma

A

t(9;14)

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12
Q

Treatment of aggressive FL

A

R-CHOP

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13
Q

Treatment of stage I or II gastric MALT lymphoma

A

Treat H pylori if present, otherwise radiation or R

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14
Q

Treatment of splenic marginal zone lympoma

A

Treat HCV if present, otherwise splenectomy or R

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15
Q

Infection associated with cutaneous MALT lymphoma

A

Borrelia Burgdorferi

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16
Q

Burkitt lymphoma cytogenetics

A

t(8;14)

17
Q

Two types of DLBCL and survival

A

germinal center B-cell - better survival

activated B-cell - worse survival

18
Q

First line treatment of primary mediastinal B cell lymphoma

A

DA-R-EPOCH

19
Q

Primary mediastinal B cell lymphoma cytogenetics

A

t(16;X)

20
Q

Morphologic description for Burkitt lymphoma

A

starry sky

21
Q

Treatment of Burkitt lymphoma

A

CODOX-M or R-HyperCVAD

22
Q

Associated disease with enteropathy-associated T-cell lymphoma

A

Celiac

23
Q

Associated diseae with extranodel NK/T-cell lymphoma

A

EBV, often in Asia

24
Q

Anaplastic large cell lymphoma mutation and cytogenetics

A

ALK subtype: t(2;5)

25
Q

Hallmark cells disease

A

Anaplastic large cell lymphoma

26
Q

Cell of origin for angioimmunoblastic T cell lymphoma

A

Follicular helper T-cell

27
Q

Impact of ALK mutation on anaplastic large cell lymphoma

A

ALK mutated has better OS

28
Q

Symptoms of angioimmunoblastic T cell lymphoma

A

Effusions, arthritis, hemolytic anemia

29
Q

Lymphoma associated with breast implants

A

Anaplastic large cell lymphoma, ALK negative

30
Q

High risk MM cytogenetics

A

t(14;16), t(14;20), del 17p

31
Q

Treatment of Mantle cell lymphoma

A

R-CHOP

32
Q

Anaplastic large cell lymphoma treatment

A

CD30+: BV with CHP

CD30-: CHOEP

33
Q

Diagnosis of onion skinning germinal centers

A

Unicentric Castleman

Medical Oncology Boards (11 decks)

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