GI Flashcards
Treatment of locally advanced esophageal cancer
Neoadjuvant chemoradiation with carbo and paclitaxel (no traztuzumab)
Second line therapy for metastatic esophageal cancer
Ramucirumab
First line therapy for metastatic esophageal cancer
FOLFOX+/- Traztuzumab
Risk factors for adenocarcinoma of esophagus (3)
Obesity, Barret’s, GERD
Risk factors for squamous cell carcinoma of esophagus
Smoking, alcohol, ionizing radiation
Treatment of local esophageal cancer in poor surgical candidate
Endoscopic mucosal resection
Gene for hereditary diffuse gastric cancer
CDH1
Management of hereditary diffuse gastric cancer
prophylatic gastrectomy
Management of resectable gastric cancer (2)
Neoadjuvant ECF
Adjuvant 5FU + radiation
Treatment of HER2 mutated metastatic gastric cancer
trastuzumab + cisplatin/5FU
Treatment of HER2- metastatic gastric cancer
ECF or FOLFOX
Second line treatment of metastatic gastric cancer
ramcirumab+paclitaxel
HNPCC genes (3)
MSH2
MSH6
PMS2
FAP gene
APC
Cowden syndrome gene
PTEN