Lymphoma Flashcards
Reed-sternberg cells (popcorn cells) are indicative of what condition
Hodgkin Lymphoma
Cell line of Lymphoid stem cell
- B cells
- T cells
what virus is found in 40-50% of cases of Hodgkin Lymphoma
epstein-barr virus
Hodgkin Lymphoma presents with painless lymphadenopathy. 60% of cases have what lymph node involvement?
Mediastinal
most patients with Hodgkin Lymphoma are diagnosed in which stages
stage I and II
prognosis of Hodgkin Lymphoma
- early stages (I and II) have favorable prognosis
- presence of B symptoms have worse prognosis
how is Hodgkin Lymphoma diagnosed
- lymph node/bone marrow biopsy showing reed sternberg cells
90% of Non-Hodgkin Lymphoma is derived from what cell type
B lymphocytes
clinical features of Non-Hodgkin Lymphoma
- Painless, persistant lymphadenopathy
- B symptoms
Non-Hodgkin Lymphoma: median age at dianosis
66 yrs
what symptoms make a lymphoma more aggressive
- rapidly growing
- B symptoms
- elevated LDH and uric acid
give some examples of aggressive lymphomas
- diffuse large B cell lymphoma
- burkitt lymphoma
- adult T cell leukemia/lymphoma
how do you diagnose Non-Hodgkin Lymphoma
lymph node biopsy
treatment of indolent Non-Hodgkin Lymphoma
radiation alone
treatment of aggressive Non-Hodgkin Lymphoma
- chemotherapy
- immunotherapy
