Lymphoid II Flashcards

1
Q

lymph nodes

A

line of defense against antigens which penetrate the epithelium and MALT and gain access to underlying connective tissue

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2
Q

components of lymph nodes

A

dense connective tissue capsule, reticular fibers, macrophages, reticular cells

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3
Q

afferent lymphatics

A

pierce the outer connective tissue capsule and deposit lymph in the subcapsular sinus

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4
Q

subcapsular sinus

A

continuous with cortical and medullary sinus, where lymph enters

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5
Q

hilum

A

location of the draining efferent lymph

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6
Q

lympathic sinuses are line with ____ _____ that permits cells and antigens to enter the node

A

discontinuous endothelium

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7
Q

nodules are found in what region of the lymph nodes?

A

outer region of the cortex

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8
Q

paracortex

A

devoid of nodules and is T cell rich (thymus dependent zone)

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9
Q

high endothelial venules

A

in the paracortex, allows circulating lymphocytes to enter the lymph node

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10
Q

selectins

A

allow lymphocytes to home in on the lymph nodes and crawl through the walls

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11
Q

medullary cords

A

loose CT (containing reticular fibers), highly cellular

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12
Q

medullary sinuses

A

venous channel running between cords, distontinuous endothelium, traversed by reticular fibers

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13
Q

paracortical reaction

A

during a viral reaction, more selectins are expressed resulting in more lymphocytes adn swelling of the paracortical region

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14
Q

Hodgkin lymphoma

A

excess proliferation of lymphocyttes with Ree-sternberg cells

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15
Q

Reed-Sternberg cells

A

large cells with bilobed nucleus (owl eye appearance)

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16
Q

the spleen is covered by…

A

a squamous epithelium (mesothelium) and underlying is a thick connective tissue capsule

17
Q

trabecular beams

A

continuous with the capsule, penetrate the spleen

18
Q

Does the spleen have a cortex and a medulla

A

NO

19
Q

periarterial lymphoid sheath

A

of the white pulp, contains both nodular and diffuse tissue and surrounds central arteries

20
Q

Are there reticular fibers in the vessels of the spleen

A

NO (except in the marginal zone)

21
Q

marginal zone

A

region between the red and white pulp, receives blood from the central arteries and promotes antigen interactions

22
Q

red pulp

A

containts cords and sinuses, filters red blood cells

23
Q

terminal sheathed capillaries empth into…

A

the meshwork of the red pulp cords

24
Q

filtrations slits

A

holes in the endoletial venules of the sinuses that filter out mishapen red blood cells