Integument Flashcards

1
Q

epidermis (type of epithelium

A

SSKE

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2
Q

dermis

A

highly vascularized dense irregular connective tissue

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3
Q

dermal papilla

A

finger-like attachments between the dermis and epidermis

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4
Q

stratum basale

A

single layer of cuboidal cells, deepest layer of the epidermis

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5
Q

what binds cells of the stratum basale

A

desmosomes

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6
Q

basal cell carcinoma

A

overproliferation of the stratum basale layer

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7
Q

stratum spinosum

A

thickest layer of epidermis, attached by desmosomes

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8
Q

stratum granulosum

A

cells with coarse basophilic granules

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9
Q

keratohylin granules

A

granules of the cells of the stratum granulosum

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10
Q

filaggrin

A

binds tonofilaments into tonofibrils

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11
Q

loracrin

A

forms dense layer deep to plasma membrane to thicken outer wall

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12
Q

stratum corneum

A

dead cells of the epidermis, last layer

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13
Q

Langerhan cells

A

antigen presenting cells of the epidermis, no desmosomes

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14
Q

merkel cells

A

neuroendocrine cells of the epidermis that lie within the stratum basale

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15
Q

melanocytes

A

specialized cells that produce pigment, neural crest derived in the stratum basale (on the basement membrane)

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16
Q

eumelainin

A

makes black to blonde hair color

17
Q

phaeomelanin

A

makes red hair

18
Q

melanocyte stimulating hormone (MSH)

A

binds to melanocortin to produce pigments

19
Q

melanoma

A

neoplastic changes in melanocytes

20
Q

papillary dermis

A

contains blood vessels and sensory receptors (close to outside world)

21
Q

reticular dermis

A

contains glands, hair follicles, smooth muscle and other sensory structures

22
Q

eccrine sweat glands

A

secrete sweat by merocrine action, simple tubular and have secretory and duct portions

23
Q

secretory portions of eccrine glands

A

produce sweat and dermcidin

24
Q

ductal portions of eccrine glands

A

convey sweat and reabsorb sodium

25
sebaceous glands
associated with hairs and produce sebum, an oily product
26
fordyce spots
sebaceous glands of the lip
27
acne
too much sebum produces from hormones that results in bacterial colonizations
28
apocrine sweat glands
dilated lumen compared to eccrine glands (store more product), likely sources of pheromones
29
free nerve endings
fibers that reach up to the stratum granulosum, no schwann cell covering (detect temp and pain)
30
Merkel cells
detect light touch, slow adapting, the the stratum basale, have a clear cytoplasm
31
pacinian corpusles
large sensory receptors in the dermis and hypodermis have schwann cells around central axon, rapidly adapting, detect vibrations
32
meissner corpusles
just under epidermis in the dermal papille, very sensitive