Integument Flashcards

1
Q

epidermis (type of epithelium

A

SSKE

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2
Q

dermis

A

highly vascularized dense irregular connective tissue

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3
Q

dermal papilla

A

finger-like attachments between the dermis and epidermis

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4
Q

stratum basale

A

single layer of cuboidal cells, deepest layer of the epidermis

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5
Q

what binds cells of the stratum basale

A

desmosomes

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6
Q

basal cell carcinoma

A

overproliferation of the stratum basale layer

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7
Q

stratum spinosum

A

thickest layer of epidermis, attached by desmosomes

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8
Q

stratum granulosum

A

cells with coarse basophilic granules

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9
Q

keratohylin granules

A

granules of the cells of the stratum granulosum

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10
Q

filaggrin

A

binds tonofilaments into tonofibrils

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11
Q

loracrin

A

forms dense layer deep to plasma membrane to thicken outer wall

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12
Q

stratum corneum

A

dead cells of the epidermis, last layer

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13
Q

Langerhan cells

A

antigen presenting cells of the epidermis, no desmosomes

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14
Q

merkel cells

A

neuroendocrine cells of the epidermis that lie within the stratum basale

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15
Q

melanocytes

A

specialized cells that produce pigment, neural crest derived in the stratum basale (on the basement membrane)

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16
Q

eumelainin

A

makes black to blonde hair color

17
Q

phaeomelanin

A

makes red hair

18
Q

melanocyte stimulating hormone (MSH)

A

binds to melanocortin to produce pigments

19
Q

melanoma

A

neoplastic changes in melanocytes

20
Q

papillary dermis

A

contains blood vessels and sensory receptors (close to outside world)

21
Q

reticular dermis

A

contains glands, hair follicles, smooth muscle and other sensory structures

22
Q

eccrine sweat glands

A

secrete sweat by merocrine action, simple tubular and have secretory and duct portions

23
Q

secretory portions of eccrine glands

A

produce sweat and dermcidin

24
Q

ductal portions of eccrine glands

A

convey sweat and reabsorb sodium

25
Q

sebaceous glands

A

associated with hairs and produce sebum, an oily product

26
Q

fordyce spots

A

sebaceous glands of the lip

27
Q

acne

A

too much sebum produces from hormones that results in bacterial colonizations

28
Q

apocrine sweat glands

A

dilated lumen compared to eccrine glands (store more product), likely sources of pheromones

29
Q

free nerve endings

A

fibers that reach up to the stratum granulosum, no schwann cell covering (detect temp and pain)

30
Q

Merkel cells

A

detect light touch, slow adapting, the the stratum basale, have a clear cytoplasm

31
Q

pacinian corpusles

A

large sensory receptors in the dermis and hypodermis have schwann cells around central axon, rapidly adapting, detect vibrations

32
Q

meissner corpusles

A

just under epidermis in the dermal papille, very sensitive