lymphatic system histo

Question 1

cells in the reticular tissue meshwork of lymph nodes

Answer 1

1. reticular cells
2. dendritic cells
3. macrophages
4. follicular dendritic cells (FDCs)

Question 2

reticular cells secrete ____ and ____

Answer 2

reticular fibers (type III collagen); ground substance

Question 3

_____ wrap around bundles of reticular fibers; isolates structural components from parenchyma of lymphatic tissues/organs

Answer 3

elongated cytoplasmic processes

Question 4

reticular cells play a ____ role

Answer 4

supporting

Question 5

reticular cells express surface molecules and produce substances that attract:

Answer 5

T cells, B cells, and dendritic cells

Question 6

dendritic cells are ____ derived ____

Answer 6

bone marrow; APCs

Question 7

macrophages act as both ___ and ____

Answer 7

phagocytes; APCs

Question 8

follicular dendritic cells (FDCs) have multiple, thin, hairlike branching _____ that interdigitate between ____ in germinal centers

Answer 8

cytoplasmic processes; B cells

Question 9

_____ complexes adhere to FDC cytoplasmic processes via ____

Answer 9

antigen-antibody; Fc receptors

Question 10

____ of lymph node divided into cortex and medulla

Answer 10

parenchyma

Question 11

outer part of cortex, just deep to capsule

Answer 11

superficial (nodular) cortex

Question 12

between superficial cortex and medulla

Answer 12

deep cortex (paracortex)

Question 13

deep cortex (paracortex) contains the majority of ____ within the lymph node

Answer 13

T cells

Question 14

the medulla consists of cords of _____ separated by _____

Answer 14

lymphatic tissue (medullary cords); lymphatic sinuses (medullary sinuses)

Question 15

network of ____ and ____ traverses medullary cords and sinuses; serve as framework for the parenchyma

Answer 15

reticular cells; fibers

Question 16

medullary cords contain:

Answer 16

lymphocytes (mostly B cells), macrophages, dendritic cells, and plasma cells

Question 17

medullary sinuses converge near ____ and drain into _____

Answer 17

hilum; efferent lymphatic vessels

Question 18

filtration of lymph in lymph node occurs within network of interconnected lymphatic channels called ____

Answer 18

sinuses

Question 19

3 types of sinuses

Answer 19

1. subcapsular (cortical) sinus
2. trabecular sinuses
3. medullary sinuses

Question 20

about 90% of lymphocytes are conveyed in blood and enter the lymph node thru ____ in the ____

Answer 20

high endothelial venules (HEVs); deep cortex

Question 21

endothelium is almost always _____, however, in lymphatic tissues, the endothelium of postcapillary venules is ____

Answer 21

simple squamous epithelium; cuboidal

Question 22

flow of lymphocytes from blood thru lymph node

Answer 22

HEVs > deep cortex > superficial cortex > back thru deep cortex >medulla > efferent lymph vessel

Question 23

flow of lymphocytes from lymph thru lymph node

Answer 23

afferent lymph vessel > subcapsular (cortical) sinus > trabecular sinus > medullary sinus > efferent lymph vessel

Question 24

developing lymphocytes (thymocytes) in the thymic cortex occupy spaces within extensive meshwork of _____

Answer 24

epithelioreticular cells

Question 25

____ are also present within thymic cortex to phagocytose ____

Answer 25

macrophages; apoptotic T cells

Question 26

thymic medulla contains large number of ____ and ____

Answer 26

epithelioreticular cells; loosely packed T cells

Question 27

_____ form the most characteristic feature of the medulla, which is _____

Answer 27

type VI epithelioreticular cells; thymic (Hassall’s) corpuscles