Lymphatic System - Histo Flashcards

1
Q

What are the three major functions of the Lymphatic System?

A

drain excess interstitial fluid to return blood to maintain blood volume
immune response
provide an alternative transportation route for hormones, nutrients and waste

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2
Q

What are the seven components of the lymphatic system?

A
  1. diffuse lymphatic tissue
  2. lymph nodules
  3. lymph nodes
  4. spleen
  5. bone marrow
  6. thymus
  7. lymphatic vessels
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3
Q

What is the definitive cell of the lymphatic system?

A

lymphocyte

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4
Q

What are three types of lymphocytes?

A

B cells, T Cells and NK cells

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5
Q

Which cell differentiate in the thymus, attach and destroy cells, are involved with cell-mediated immunity, and make up 60 - 80% of circulating lymphocytes?

A

T cells

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6
Q

What cell was first recognized in the bursa of Fabricius in birds, produce and secrete antibodies, are involved in humoral immunty and make up 20 - 30% of circulating lymphocytes?

A

B cells

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7
Q

___ ___ cells kill certain transformed cells and make up 5 - 10% of circulating lymphocytes.

A

Natural Killer

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8
Q

What tissue type has an accumulation of lymphocytes in the lamina propria of the alimentary canal, respiratory, urinary, and reproductive tracts?

A

diffuse lymphatic tissue

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9
Q

Diffuse lymphatic tissue has no surrounding ___ and houses ___ cells and ___.

A

capsule; plasma; eosinophils

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10
Q

Lymphatic nodules have no surrounding ___, are sharply defined, contain a meshwork of ___ fibers and have lymphocytes, plasma cells and eosinophils.

A

capsule, reticular

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11
Q

A secondary nodule has a ___ center with follicular ___ cells and a ___ zone.

A

germinal; dendritic; mantle

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12
Q

What is an aggregate of primarily small lymphocytes?

A

primary nodule

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13
Q

T/F. Normally, lymphatic nodules are found grouped together however in certain areas of the alimentary canal they are found randomly dispersed and my themselves.

A

False, Normally, lymphatic nodules are found randomly dispersed and by themselves however, in certain locations of the alimentary canal they are grouped together.

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14
Q

Give two examples of aggregated lymphatic nodules.

A
  1. Tonsils

2. Peyer’s patches

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15
Q

Which aggregated lymphatic nodule is found in the ileum?

A

Peyer’s patches

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16
Q

___ create a ring around the entrance to the oropharynx and the nasopharynx.

A

Tonsils

17
Q

Where would you find lymph nodes and what is the function?

A
capsuled organs along pathways of lymphatic vessels
function to filter system
18
Q

What three areas of the lymph node make up the stroma?

A

capsule, trabeculae, and reticular tissue/meshwork

19
Q

What parts make up the lymph node’s parenchyma?

A

cortex and medulla

20
Q

Where are the germinal centers of a lymph node located?

A

Cortex - superficial (nodular) cortex - lymphatic nodules - secondary area

21
Q

The ___ can be divided into the cords and sinuses.

A

medulla

22
Q

What are the four cells of the reticular meshwork?

A

reticular cells, dendritic cells, macrophages, and follicular dendritic cells

23
Q

List the flow of lymph through the lymph node.

A

afferent lymph vessel - subcapsular (cortical) sinus - trabecular sinus - medullary sinus - efferent lymph vessels

24
Q

The thymus is the site of thymic cell ___, a process through which T cells mature and differentiate into immunocompetent T cells.

A

education

25
Q

What is the function of the spleen?

A

it filters and monitors the blood immunologically

26
Q

The ___ pulp of the spleen consists of blood-filled venous sinuses surrounded by cords of splenic tissue called splenic (___) cords, that contain RBCs, macrophages, lymphocytes, plasma cells, and granulocytes.

A

red; Billroth’s

27
Q

What is the function of the red pulp?

A

blood filtration (removal of materials, antigens, and worn-out or defective RBCs, WBCs, and platelets)

28
Q

White pulp consist mostly of ___ that aggregate around branches of the splenic ___ (called ___ ___) creating ___ ___ ___ (PALS).

A

lymphocytes; artery; central arteries; periarterial lymphatic sheaths

29
Q

What is the function of the white pulp?

A

To carry out immune functions similar to lymph nodes