Lymphatic System Flashcards
Lymphatic vessels
extensive and complex network, everywhere in the body EXCEPT for the brain, bone marrow, and avascular tissue (epithelia and cartilage)
“start to finish” pathway of LS
porous blind-ended capillaries located in body tissues – form large vessels that ultimately connect with large veins in the neck
What do lymphatic vessels carry?
fluid lost from vascular capillary beds during nutrient exchange, cell debris, pathogens, cell products (hormones), lymphocytic cells
Two types of fluid in lymphatic vessels
lymph and chyle
Lymph
clear, colorless liquid
Chyle
milky, opaque liquid containing chylomicrons (protein coated lipid droplets from the GI epithelium, released via lacteals)
By what mechanism(s) does fluid move through the lymphatic system?
- valves in the vessels (maintain unidirectional flow)
- contraction of adjacent skeletal muscle/arterial pressure
Lymph nodes
small encapsulated “interruptions” (honeycomb of reticular connective tissue) in the vessels of the lymphatic system that contain lymphocytes and macrophages - essentially slow, efficient filters
What do Lymph nodes detect?
foreign antigens
List the lymph nodes in the body/
(from superior to inferior) * indicates can be palpated cervical* tracheal axillary* deep inguinal* femoral*
Lymphatic Trunks and Ducts
vessels converge to form trunks/ducts that drain to venous system at the brachiocephalic trunk (where the internal jugular veins meet subclavian veins)
Right vs. Left side of body drainage
Right half of head, right upper limb, right upper half of torso drains to right side of neck
Left half of head, left upper limb, left upper half of torso, lower half of torso and legs drain to the left side of the neck
Clinical relevance of lymph nodes (ITC)
lymph nodes can become swollen, tender, and inflamed when activated (exposed to a foreign antigen or pathogen) - can be palpated and physicians are able to track the course of infection and disease progression
cancer - b/c lymph nodes are slow working, if a metastatic cell reaches the node, it can become lodged and form secondary tumors that may need removed if clinically symptomatic
Lymphoma (ITC)
primary lymph node malignancy