Lymphatic / immune system Flashcards
interstitial fluid that flows through the lymphatic system
Lymph
What are lymph’s composed of
- Lymph vessels
- lymph nodes
- lymph glands
- lymphoid tissue
The Lymph organs consist of :
tonsils
adenoids & vermiform
appendix & spleen
thymus gland & peyer patches
contain a single, large nucleus.
- largest phagocytic WBC & transform into macrophages when in lymphatic tissue
Monocytes
two types : T lymphocytes (T cells) and B lymphocytes (B cells)
Lymphocytes
- Also called lymphs
Very large monocytes that grew in size once they migrated out of the bloodstream and lived in the tissues.
- Engulf foreign particles, microorganisms, and cell debris.
Macrophages
What quadrant is the spleen located
the upper left quadrant.
- Removes old RBC’s q 90-120 days
Where is the Thymus gland located & what lymph’s does it develop ?
- located in the mediastinum
- Developes T lymphocytes
- Helps protect the entrances to the respiratory & digestive system
- are lymphatic tissue
Tonsils
located in the right lower quadrant and attached to the ascending colon of your large intestine
Vermiform appendix
What are the common cells found in the lymphatic system ?
WBC’s
composed of organs, tissues, cells, & chemical messengers
Immune system
your chemical messengers
Cytokines
What are Neutrophils , Eosinophils , & Basophils characterized by ?
their heavily granulated cytoplasm
What are the Granular WBC’s ?
- Neutrophils
- Eosinophils
- Basophils
What are the Agranular WBC’s ?
- Monocytes
- Macrophages
Primary function is to differentiate what is “self” & what is “foreign” & then destroy anything that is foreign in the body.
Immune system level of defense
Nonspecific immunity is also known as :
innate immunity
Specific immunity is also known as :
adaptive immunity
Many ways the body protects itself from pathogens w/o having to recognize them
Nonspecific immunity
Methods of protection : (first)
-Physical
-Reflexes
-Chemical
Second line of defense :
- Phagocytosis
- Inflammation
- Pyrexia = fever
- Protective proteins
- (NK) natural killer cells
Immunoglobulin –
Mostly found in circulating blood and tissues.
- Crosses the placenta to the unborn baby.
- provides the majority of antibody-based immunity.
IgG
Immunoglobulin –
Produced early in the immune response before IgG.
IgM
Immunoglobulins –
Found in the gastrointestinal, urinary, and respiratory systems.
-It is secreted in tears, saliva, and breast milk.
IgA
Immunoglobulins –
Created in response to an allergic reaction and multicellular organisms (parasitic worms).
IgE
Immunoglobulins –
Found in low levels in the serum.
- May interact with mast cells and basophils.
IgD
also called antibody-mediated immunity, involves the production of B lymphocytes (B cells) and antibodies.
Humoral immunity
- response involves T cells, which are responsible for destroying cells infected with antigens (viruses) and abnormal body cells, such as cancerous cells and transplanted tissues.
- Cell-mediated immunity is also a complex response.
Cell - mediated immunity
(anaphylactic response)
- Considered an immediate allergic reaction.
Type 1
(cytotoxic-mediated response)
- Causes damage to the body’s own tissues.
Type 2
(immunocomplex reaction)
- Causes inflammation and tissue damage.
Type 3
(cell-mediated hypersensitivity)
- A delayed response caused by a cell-mediated response.
Type 4
the body is exposed to the antigen and the body “actively” produces the antibodies.
- This type of immunity is slow to start working, but it can last a lifetime.
Active immunity