Lymphatic,endocrine,body Efense Exam Flashcards
Action chemotaxis
movement toward or away from a chemical stimulus. Chemotaxis is a cellular function, particularly of neutrophils and monocytes, whose phagocytic activity is influenced by chemical factors released by invading microorganisms.
ACTH
Adrenocorticotropic hormone; a hormone that is produced by the anterior lobe of the pituitary gland and that stimulates the secretion of cortisone, aldosterone, and other hormones by the adrenal cortex. Also called adrenocorticotropin, adrenotropin, corticotropin.
ACTION DETERMINT OF ADAPTIVE IMMUNE SYSTEM
:antigenic determinants-only certain parts of an entire antigen are immunogenic
- antibodies and activated lymphocytes bind to the antigenic determinants
- most naturally occurring antigens have numerous antigenic determinants that:mobilize several different lymphocyte populations,and form different kinds of antibodies against it
- large chemically simple molecules like plastics have little or no immunogenicity
ACTION DIAPEDESIS
The movement or passage of blood cells, especially white blood cells, through intact capillary walls into surrounding body tissue. Also called migration.
Action margination
The adhesion of white blood cells to the endothelial cells of blood vessels that occurs at the site of an injury during the early phases of inflammation.
Action phagocytosis
The engulfing and ingestion of bacteria or other foreign bodies by phagocytes.
Action of parathyroid
four small endocrine bodies in the region of the thyroid gland; they contain two types of cells: chief cells and oxyphils. Chief cells are the major source of parathyroid hormone (PTH), the secretion of which is dependent on the serum calcium level. Through a closed-loop feedback mechanism a low serum calcium level stimulates secretion of PTH; conversely, a high serum calcium level inhibits its secretion. The essential role of PTH is maintenance of a normal serum calcium level in association with vitamin D and calcitonin. It does this by exerting its effects on bone, kidney, and gastrointestinal tract. In bone, it enhances bone resorption by increasing digestion of the bone matrix by osteoclasts, which produces calcium that gets released into the bloodstream. In the kidney, PTH increases the excretion of phosphate and the reabsorption of filtered calcium. In the intestine, it increases intestinal absorption of calcium
Action of steroids
A group of drugs that includes the corticosteroids, similar to hormones produced by the adrenal glands, and used to relieve inflammation and itching.
Activation of T cells
A type of white blood cell produced in the thymus gland. T cells are an important part of the immune system. Infants born with an underdeveloped or absent thymus do not have a normal level of T cells in their blood.
ADH
vasopressin anterior pituitary hormone; causes urine concentration by increasing resorption of solute at the distal convoluted tubule of nephron; absence of ADH causes diabetes insipidus
Aldosterone
a mineralocorticoid steroid hormone produced by the adrenal cortex with action in the renal tubule to retain sodium, conserve water by reabsorption, and increase urinary excretion of potassium.
ANGIOTENSINOGEN
a serum glycoprotein produced in the liver that is the precursor of angiotensin.
B LYMPOCYTES
type of lymphocyte that circulates in the blood and lymph and produces antibodies when it encounters specific antigens. B lymphocytes are also called B cells.
Blockage of lymphatics
Lymphatic obstruction is a blockage of the lymph vessels that drain fluid from tissues throughout the body and allow immune cells to travel where they are needed. Lymphatic obstruction may cause lymphedema, which means swelling due to a blockage of the lymph passages.
CAUSES OF SIGNS OF INFLAMMATION
:inflammation tissue response-triggered whenever body tissue is injured
- prevents spread of damaging agents to nearby tissues
- disposes of cell debris and pathogens
- sets stage for repair process
- four sign are redness swelling pain and heat
CELLS OF CHRONIC INFECTIONS
Cells can sometimes lose ability to establish self from non self(autoimmune disease), also in immunodeficiency disease cells lose ability to produce phagocytes normally
Cellular immunity
the mechanism of acquired immunity characterized by the dominant role of T cell lymphocytes. Cellular immunity is involved in resistance to infectious diseases caused by viruses and some bacteria and in delayed hypersensitivity reactions, some aspects of resistance to cancer, certain autoimmune diseases, graft rejection, and certain allergies. It does not involve the production of humoral antibody but instead involves the activation of Mo and natural killer cells
CHARACTERISTICS OF ADAPTIVE IMMUNE SYSTEM
:innate defense cells and chemicals
-body uses nonspecific celluar and chemical devices to protect itself
-phagocytes and natural killer cells
-anti microbial proteins in blood and tissue fluid
-inflammatory response enlists macrophages,mast cells,WBCs, and chemicals
2nd line of defense
CHARACTERISTICS OF ANTIBODIES
Specialized cells of the immune system which can recognize organisms that invade the body (such as bacteria, viruses, and fungi). The antibodies are then able to set off a complex chain of events designed to kill these foreign invaders.
CHARACTERISTICS OF COMPLETE ANTIGENS
one which both stimulates an immune response and reacts with the products of that response.
CHARACTERISTICS OF INFLAMMATION
Red,pain,heat,swelling
CHARACTERISTICS OF INTERFERONS
Any of a group of glycoproteins that are produced by different cell types in response to various stimuli, such as exposure to viruses, and that block viral replication in newly infected cells and, in some cases, modulate specific cellular functions.
CHARACTERISTICS OF LYMPH CAPILLARIES
are tiny thin-walled blood vessels that are closed at one end and are located in the spaces between cells throughout the body, except in the central nervous system, and in non-vascular tissues. The main purpose of these vessels is to drain excess tissue fluids from around the cell ready to be filtered and returned to the venous circulation
CHARACTERISTICS OF LYMPHOCYTES
The three major types of lymphocyte are T cells, B cells and natural killer (NK) cells. Under the microscope, lymphocytes can be divided into large granular lymphocytes and small lymphocytes. Large granular lymphocytes include natural killer cells (NK cells). Small lymphocytes consist of T cells and B cells.
CHARACTERISTICS OF PASSIVE IMMUNITY
the transfer of active humoral immunity in the form of readymade antibodies, from one individual to another. Passive immunity can occur naturally, when maternal antibodies are transferred to the fetus through the placenta, and can also be induced artificially, when high levels of human (or horse) antibodies specific for a pathogen or toxin are transferred to non-immune individuals. Passive immunization is used when there is a high risk of infection and insufficient time for the body to develop its own immune response, or to reduce the symptoms of ongoing or immunosuppressive diseases.[1]
CHARACTERISTICS OF PHAGOCYTIC CELLS
Engulf microorganism,cell debris,or foreign matter
CHARACTERISTICS OF THYMUS GLAND
a specialized organ of the immune system. The only known function of the thymus is the production and “education” of T-lymphocytes (T cells), which are critical cells of the adaptive immune system. The thymus is composed of two identical lobes and is located anatomically in the anterior superior mediastinum, in front of the heart and behind the sternum.
CHARACTERISTICS OF TROPIC HORMONES
those hormones of the anterior lobe of the pituitary that affect the growth, nutrition, or function of other endocrine glands (for example, TRH, ACTH).
CONTROL OF TSH
A hormone secreted by the pituitary gland that controls the release of T4 by the thyroid gland.
CONTROLLING FACTORS OF ADRENAL MEDULLA
The inner part of the adrenal gland. The adrenal medulla produces the hormones epinephrine (adrenaline), which stimulates the heart, tightens blood vessels, and relaxes some smooth muscles; and norepinephrine, which has similar effects.
CONTROLLING FACTORS OF PANCREAS
a large, elongated, racemose gland lying transversely behind the stomach, between the spleen and duodenum. Its external secretion contains digestive enzymes. One internal secretion, insulin, is produced by the beta cells, and another, glucagon, is produced by the alpha cells. The alpha, beta, and delta cells form aggregates, called islands of Langerhans.
CONTROLLING FACTORS OF THYROID
A gland in the neck overlying the windpipe that regulates the speed of metabolic processes by producing a hormone, thyroxin.
CONTROLLING FACTORS PITUITARY
A gland located at the base of the brain that produces a number of hormones, including those that regulate growth and reproductive functions. Overproduction of the pituitary hormone called growth hormone (GH) is responsible for the condition known as acromegaly.
CONTROLLLING FACTORS OF PARATHYROID
parathyroid glands four small endocrine bodies in the region of the thyroid gland; they contain two types of cells: chief cells and oxyphils. Chief cells are the major source of parathyroid hormone (PTH), the secretion of which is dependent on the serum calcium level. Through a closed-loop feedback mechanism a low serum calcium level stimulates secretion of PTH; conversely, a high serum calcium level inhibits its secretion. The essential role of PTH is maintenance of a normal serum calcium level in association with vitamin D and calcitonin
Cortisol
cortisol /cor·ti·sol/ (-sol) the major natural glucocorticoid elaborated by the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has mineralocorticoid activity. See hydrocortisone for therapeutic uses.
CYTOTOXIC T CELLS
a lymphocyte that lacks B or T cell markers. It is the effector cell of antibody-dependent cell-mediated cytotoxicity; it recognizes antibodies on target cells and lyses those cells through a cell-cell interaction that does not require complement. Compare killer T cells, natural killer cell. See also null cell.
Define antibodies
Specialized cells of the immune system which can recognize organisms that invade the body (such as bacteria, viruses, and fungi). The antibodies are then able to set off a complex chain of events designed to kill these foreign invaders.
Define appendix
- a small appendage near the juncture of the small intestine and the large intestine (ileocecal valve). An apparently useless structure, it can be the source of a serious illness, appendicitis. Called also vermiform appendix. adj., adj appendic´eal.
Define enzymes
Organic substances (proteins) composed of amino acids that trigger and regulate chemical reactions in the body. There are over 700 identified human enzymes.
Define fever
Over 100
Define first line of defense
Or Innate, surface barriers skin and mucosa
Define haptens
hapten /hap·ten/ (hap´ten) partial antigen; a specific nonprotein substance which does not itself elicit antibody formation but does elicit the immune response when coupled with a carrier protein.hapten´ic
Define immunocompetent
Having a normal immune response
Define innate immune sys
Fist line of defense so mechanical barriers
Define lymph
- A clear, watery, sometimes faintly yellowish fluid derived from body tissues that contains white blood cells and circulates throughout the lymphatic system, returning to the venous bloodstream through the thoracic duct. Lymph acts to remove bacteria and certain proteins from the tissues, transport fat from the small intestine, and supply mature lymphocytes to the blood.
Define lymph nodes
n.
Any of the small bodies located along the lymphatic vessels, particularly at the neck, armpit, and groin, that filter bacteria and foreign particles from lymph fluid. During infection, lymph nodes may become swollen with activated lymphocytes. Also called lymph gland.