Lupus Nephritis Flashcards
1
Q
Who’s is more likely to have lupus nephritis
A
African American female adolescents
2
Q
What is the patho behind lupus nephritis
A
Deposits of circulating immune complexes activate complement cascades, leukocyte infiltration, activation of procoagulant factors, cytokine release
3
Q
S/S of lupus nephritis
A
Proteinuria, hematuria, HTN, WBC casts
4
Q
Diagnostics for lupus nephritis
A
Renal biopsy
Anti DNA antibodies
Hypocomplementemia
5
Q
What are complements
A
Proteins activated by pathogens or antibodies
6
Q
What is the treatment plan for lupus nephritis
A
High dose steroids, cyclophosphamide or mycophenolate
Eventually lower the steroid doses
Consult nephrology
