Lungs Flashcards

1
Q
  • Obstruction of upper fetal airway (CHAOS)
  • Airways become dilated, lungs enlarge and fill with fluid; diaphragm flattened or inverted, fetal ascites and/ or hydrops
  • Tx: dilation
A

Laryngeal atresia

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2
Q
  • Abnormal communication between trachea and esophagus 2/2 failure of foregut endoderm to proliferate quickly enough in relation to the rest of the embryo
  • Associated with esophageal atresia and polyhydramnios
  • Clinical features: excessive saliva or mucus accumulation in nose and mouth; gagging and cyanosis after swallowing milk; abdominal distension after crying; reflux of gastric contents into the lungs causing pneumonitis
  • Dx: inability to pass a catheter into stomach and radiographs demonstrating air into infants stomach
A

Tracheoesophageal fistula

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3
Q

Complete absence of UL lung or lobe and accompanying bronchi d/t failure of respiratory bud to split into R/L buds

A

Pulmonary agenesis

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4
Q
  • Insufficient amniotic fluid production (<500mL)
  • Associated with renal agenesis or failure

Severe/ chronic conditions → pulmonary hypoplasia

  • Restriction of fetal thorax 2/2 uterine pressure
  • Decreased hydraulic pressure on the lungs affects stretch receptors
  • Risk significantly increased with oligohydramnios <26 weeks
  • Potters sequence (wide nasal bridge, limb hypoplasia, nasal flairing, renal failure)
A

Oligohydramnios

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5
Q
  • Rapid labored breathing shortly after birth 2/2 surfactant deficiency
  • Type II alveolar cells incapable of producing surfactant
  • Lungs are underinflated, alveoli contain fluid and resemble glassy membrane
  • Clinical signs: tachypnea; nasal flaring; suprasternal, intercostal, or subcostal retractions, grunting; cyanosis
A

Respiratory distress syndrome

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6
Q
  • Fluid or air filled cysts thought to be formed by dilation of terminal bronchi
  • Causes disturbance in bronchial development during late fetal life
  • Clinical signs: wheezing, cyanosis, difficulty breathing
A

Congenital lung cysts

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