25. MI Flashcards
sx indicating MI
- chest discomfort: heavy, crushing, pressure in the left retrosternal area across the chest; radiating in neck, jaw, L arm/shoulder, epigastrium, or between shoulder blades
- associated sx: nausea, emesis, diaphoresis, dyspnea
which populations are of particular concern for a silent or atypical MI
diabetics, elderly women
pathophysiology of an MI
narrowing of coronary arteries d/t erosion, fissuring, or rupture of plaque causing thrombus formation
what can a partial occlusion of coronary arteries cause
unstable angina (new and worsening CP) or NSTEMI
describe the progression of CAD/ACS
normal heart –> stable angina –> unatable angina –> NSTEMI –> STEMI
what would an ECG indicating subendocardial injury show?
epicardial ischemia/ infarction?
R waves normal, ST segment elevated, T wave peaked
diminishing amplitude of R wave, marked ST elevation
what is ischemia and how does it show up on ECG
- deficient blood supply, impairing repolarization
- inverted T wave
what is cardiac injury and how does it show up on ECG
- deficient blood supply, impairing ability to fully polarize
- ST segment shift
what is infarction and how does it show up on ECG
- dead tissue, unable to depolarize
- widened Q waves
when are troponin levels detectable, when do they peak and for how long can levels be elevated in relation to cardiac necrosis
- detectable 1-4 hours after onset of AMI
- peak 10-24 hours
- persist 5-14 days
*renal failure can also cause false positive
how can a NSTEMI be diagnosed
- elevated troponin, CK, CK/MB
- ST depression of T wave inversion in contigious leads
a subendocardial infaction is basically the same thing as ___
NSTEMI
how much is the ST segment elevated in STEMI (men vs women)
elevated 2+ mm in men (1.5+ mm in women) in absence of LVH
or 1+ mm in more than 2 contigious leads
what other cardiac issue may obscure ST elevation analysis
new LBBB, may need serial tracings to determine
ischemia causes ___ d/t ___
inverted T waves d/t altered repolarization