Lung cancer Flashcards

1
Q

Presenting complaints about a possible lung cancer case

A
  • Haemoptysis (Bright red blood in sputum)
  • Increase in cough and breathlessness
  • Ulceration
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2
Q

How would you investigate a possible case of lung cancer?

A
  • Fresh sputum for cytology
  • Bronchoscopy and biopsy
  • Possible CT scan for assessment of tumour size and local invasion
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3
Q

What treatment would you use for a squamous cell carcinoma and why

A

Radiotherapy as it will be radiosensitive

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4
Q

When would surgery be unsuitable

A
  • Patient already in respiratory distress (eg due to emphysema)
  • INadequate respiratory reserve
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5
Q

Where does a squamous cell carcinoma arise

A

IN metaplastic epithelium

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6
Q

What is a squamous cell carcinoma in the lung related to

A

SMoking

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7
Q

What is an adenocarcinoma of the lung related to

A

Not smoking

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8
Q

How is an adenocarcinoma of the lung presented as

A

Pleural effusion (build up of water between pleura)

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9
Q

How is an adenocarcinoma of the lung diagnosed

A

Image-guided biopsy

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10
Q

What is ‘stridor’

A

High pitched wheezing

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11
Q

What should happen if a patient has stridor

A

Urgent admission

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12
Q

What is small cell carcinoma of the lung derived from and what is this related to

A

Pulmonary neuroendocrine cells

-Smoking related

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13
Q

How is small cell carcinoma of lung presented as

A

Because of local invasion of vital structures (SVC AND OBSTRUCTION OF BRONCHUS)

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14
Q

How os small cell carcinoma of lung diagnosed by

A

Cytology and biopsy

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15
Q

What is the prognosis of a small cell carcinoma of the lung like

A

Really bad

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16
Q

How are lung cancers classified

A

+Small cell carcinomas
+Non-small cell carcinomas
-Squamous cell carcinoma
-Adenocarcinoma

Others: Large cell carcinoma

17
Q

What are other presentations of lung cancer

A

Cancer cachexia

Stridor

Clubbing

Hoarseness (recurrent laryngeal nerve involvement)

Wasted muscles of hand

Low sodium and plasma osmolality and high urine osmolality

Ectopic ACTH

HYpercalcaemia

Neurological syndromes