Lung Cancer

Question 1

Lung cancer metastis often land where

Answer 1

adrenal gland

Question 2

Small cell carcinoma

paraneoplastic syndrome(s)

Answer 2

SIADH

ACTH → increased cortisol levels

Eaton-Lambert syndrome

⇒ antibodies against presynaptic VG Ca²⁺ channels

Question 3

Squamous cell carcinoma

paraneoplastic syndrome(s)

Answer 3

PTHrp secretion

elevated serum Ca²⁺

*ominous

*and most common lung cancer in smokers

Question 4

Histological findings of squamous cell carcinoma

Answer 4

kerain pearls

intercellular bridges

Question 5

Adenocarcinoma

histological findings

Answer 5

glands

and/or

mucin

Question 6

Adenocarcinoma

location

Answer 6

peripheral growth

(makes sense–pleura has glands)

Question 7

Large cell carcinoma

location

Answer 7

central or peripheral

Question 8

Large cell carcinoma

characteristics

Answer 8

poorly differentiated large cells

central or peripheral location

poor prognosis

smoking association

Question 9

Carcinoid tumor

histology

Answer 9

well-differentiated neuroendocrine cells

stain chromogranin +

Question 10

Carcinoid tumor

classic manifestation

Answer 10

polyp-like mass in bronchus

Question 11

Carcinoid tumor

paraneoplastic syndrome(s)

Answer 11

carcinoid syndrome

5-HT secretion

flushing, diarrhea, wheezing

Question 12

Metastisis from lung locations

Answer 12

breat and colon

Question 13

“Cannon-ball” lung nodules

Answer 13

metastisis to lung

from other cancers

Question 14

Bronchioalveolar carcinoma

histology

Answer 14

columnar cells

arise from Clara cells

Question 15

Bronchioalveolar carcinoma

origin

Answer 15

Clara cells