Lower Resp - Leukotriene Receptor Antagonists

Question 1

Leukotriene Receptor Antagonists

Drug Names

Answer 1

“-lukast”
Zafirlukast*
Montelukast

Question 2

Leukotriene Receptor Antagonists

Action

Answer 2

Blocks receptors for production of leukotrienes

Question 3

Leukotriene Receptor Antagonists

Indications

Answer 3

• Prophylaxis

- Bronchial asthma

Question 4

Leukotriene Receptor Antagonists

Contraindications and Cautions

Answer 4

CI: acute asthma attacks

Cautions: hepatic and renal impairment, P & L

Question 5

Leukotriene Receptor Antagonists

Adverse Effects

Answer 5

URI, pharyngitis, cough, HA, dizzy, NVD, abdominal pain, increased liver enzymes, generalized pain, fever, mood changes

Question 6

Leukotriene Receptor Antagonists

Drug-Drug Interactions

Answer 6

Propranolol, theophylline, terfenadine, warfarin, calcium channel blockers, cyclosporine, aspirin

Question 7

Leukotriene Receptor Antagonists

Specific Nursing Conditions

Answer 7

Abdominal exam
Take on empty stomach
Avoid aspirin
Not for acute attacks
Use continuously