Cardiotropic Agents - Cardiac Glycosides

Question 1

Cardiotropic Agents - Cardiac Glycosides

Drug Name

Answer 1

Digoxin

Question 2

Cardiotropic Agents - Cardiac Glycosides

Actions

Answer 2

Allows calcium to enter cells creating positive inotropic effects
Increases renal perfusion with diuretic effect
Decrease renin release
Slows AV node
Decreases BP
Decreases cardiac workload

Question 3

Cardiotropic Agents - Cardiac Glycosides

Indications

Answer 3

HF

AF

Question 4

Cardiotropic Agents - Cardiac Glycosides

Contraindications

Answer 4

Allergy
ventricular tachycardia
heart block
sick sinus syndrome
acute MI
P & L

Question 5

Cardiotropic Agents - Cardiac Glycosides

Adverse Effects

Answer 5

HA, weakness, vision changes - yellow halo
GI upset - anorexia
Bradyarrhythmia

Question 6

Cardiotropic Agents - Cardiac Glycosides

DDI

Answer 6

Verapamil, amiodarone, quinidine, cyclosporine, K+ loss diuretics, charcoal, methotrexate

Question 7

Cardiotropic Agents - Cardiac Glycosides

Specific Nursing Considerations

Answer 7

Check reflexes
Avoid IM injection
Monitor apical pulse for full min - hold for <60 bpm
Admin IV over 5 minutes minimum
Weigh pt everyday same time AM
Emergency equipment: K+ salts, lidocaine, phenytoin, atropine, cardiac monitor
Obtain digoxin levels ( 2-3)