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Pharm 155 > Antiemetic Agents - Substance P/Neurokinin 1 Receptor Antagonists > Flashcards

Antiemetic Agents - Substance P/Neurokinin 1 Receptor Antagonists Flashcards

1
Q

Antiemetic Agents - Substance P/Neurokinin 1 Receptor Antagonists
Drug Names

A

Aprepitant*

Rolapitant

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2
Q

Antiemetic Agents - Substance P/Neurokinin 1 Receptor Antagonists
Action

A

Acts directly in CNS to block receptors assoc with N/V

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3
Q

Antiemetic Agents - Substance P/Neurokinin 1 Receptor Antagonists
Indications

A

Combination treatment with other antiemetics

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4
Q

Antiemetic Agents - Substance P/Neurokinin 1 Receptor Antagonists
Contraindications

A

Allergy

P & L

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5
Q

Antiemetic Agents - Substance P/Neurokinin 1 Receptor Antagonists
Adverse Effects

A

Anorexia, fatigue, constipation, diarrhea, elevated liver enzymes, dehydration

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6
Q

Antiemetic Agents - Substance P/Neurokinin 1 Receptor Antagonists
DDI

A

Warfarin

Contraceptives

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Pharm 155 (17 decks)

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