Lower GI Flashcards
Differentiate the appearance of gut mucosal inflammation in UC and Crohn’s
UC: continuous through colon
Crohn’s: patchy, ‘skip lesions’
Differentiate the appearance of stool in UC and Crohn’s
UC: Bloody diarrhoea, may have mucous
Crohn’s: diarrhoea, may have blood
Differentiate the flare pattern of Crohn’s and UC
Crohn’s: systemically unwell
UC: Well in between attacks
How does blood in stool appear in IBD?
Mixed in
Where are Crohn’s patients most likely to get pain and why?
Right iliac fossa
Due to terminal ileitis
What is pyoderma gangrenosum?
Skin condition causing deep, necrotic ulcers
Recall 6 extra-articular manifestations of IBD, and one of UC specifically
Erythema nodosum Clubbing Aphthous ulcers Arthritis Pyoderma gangrenosum Uveitis UC specifically: PSC
What is the first-line investigation for suspected IBD?
Stool sample
What is the investigation required for definitive diagnosis of UC?
Colonoscopy and biopsy
What is the lead pipe sign in radiology?
Complete loss of haustral markings in the colon due to inflammation
Recall 2 causes of toxic megacolon
IBD
C diff
Recall the management of UC
Conservative: no
Medical for inducing remission: aminosalicylates
Medical for maintaining remission: azothioprine/ methotrexate/ cyclosporin
Surgery: can be curative
Recall the management of Crohn’s
Conservative: no
Medical for inducing remission: corticosteroids
Medical for maintaining remission: azothioprine, methotrexate, cyclosporin AND infliximab
Surgery can not cure
Recall 3 signs of coeliac disease
IgA deficiency
Anaemia
Dermatitis herpetiformis
What is dermatitis herpetiformis?
Pruritic, erythematous paupulovesicularrash that typically presents on elbows