Lousielle extras Flashcards
Charles Law
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Boyles Law
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STPD
Standard Temp Pressure Dry
Difference between anatomical and physiological Dead space
Anatomical: 150mL or 1/3 VT. COnducting zone of trachea to terminal bronchiole
Physiological: Alveolar space that is ventilated but not perfused and therefore doesn’t undergo gas exhange + normal dead space
Bohrs equation and what does this equation assume?
1) assumes that inspired CO2= 0
2) assumes that VT= VA + VD
3) PACO2 = PaCO2
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Poiseuille-Hagen Law. What does this approximate?
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Laminar flow
Resistance equation
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laminar flow vs turbulent flow
In turbulent, a much larger pressure gradient is required to achieve a given flow
To get air in you need to overcome lungs ______ and _________
To get air in you need to overcome lungs compliance and resistance to airflow
Saturation water pressure
47mmHg or 6.3kPa
Units of compliance
L.(cmH20^-1)
Compliance is dependent on
1) elasticity of the lung
2) air-water surface tension
Cspecific equation
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Laplace’s Law
P proportional T/r
What can increase compliance?
Pulmonary oedema
Fibrosis
Deficiency of pulmonary surfactant
Atelectasis
FRC is ___% of TLC
FRC is ~40% of TLC
Draw the ‘Equation of motion’ for both elastance AND compliance
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Daltons Law
The total pressure exerted by a mixture of gases is equal to the sum of partial pressures of each individual gas present
PO2gas = PO2liquid = FO2 x PB
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Henrys law
Content = solubility x pressure
Solubility of CO2 vs O2
Solubility of CO2 = 60mL/L (100mmHg)
Solubility of O2 = 3mL/L (100mmHg)
Types of Anatomical Shunts
1) Most of the bronchial circulation
2) Thesbian component of the coronary circulation
3) Pulmonary Arteriovenous fistula
4) Patent Ductus arteriosis
5) Patent foramen ovale
Physiological Shunts
any admicture of mixed (systemic) blood with blood from the pulmonary capillaries
