Long term complications of GORD Flashcards
1
Q
2 complications of GORD
A
- Barret’s disease
2. oesophageal adenocarcinoma cancer
2
Q
what is barrets disease
A
acid from stomach enters the oesophagus - causing a change in the oesophageal epithelium
3
Q
describe the change in the oesophageal epithelium in barrets disease
A
stomach (simple columnar)
oesophagus (stratified squamous)
4
Q
what is the name given to the oesophagogastric junction in barrets disease patients
A
squamocolumnar junction
5
Q
where does oesophageal adenocarcinoma occur?
A
distal oesophagus
6
Q
what causes oesophageal adenocarcinoma
A
mutations in the oesophageal cells caused by abnormal acid exposure
7
Q
what 3 conditions can be caused from acid entering the lungs
A
dyspnoea , asthma , aspiration pneumonia