Locoregional Analgesia Flashcards
(97 cards)
What are 3 examples of locoregional blocks?
- placement or deposition of substances near nerves, nerve roots, ganglia, or spinal cord segments
- placement of substances within affected joints
- placement of substances near or around affected structures, like tendons, bursa, or trigger points
What are some reasons that more veterinarians do not utilize locoregional anesthesia? What are 3 common adverse effects?
- time to learn and perform
- invasiveness
- cost
- urinary retention
- impaired motor function
- hair regrowth issues
What are the 3 most common means of providing local blocks and epidurals?
- blind technique - use anatomical landmarks
- neurostimulation block - microcurrent and motor response
- echo or ultrasound
What operative and post-operative benefits are associated with the use of locoregional blocks? What is an additional use for it?
OP - reduced MAC, reduced anesthesia need, analgesia
POST-OP - ambulation, appetite, reduced operative pain
chronic pain reduction
What potential toxicity occurs first with the use of locoregional blocks? What are some signs?
CNS
- dizziness
- tinnitus
- disorientation
- seizures
What potential toxicity occurs after CNS toxity associated with locoregional blocks? What medication most likely causes this? What are some signs?
cardiovascular
bupivicaine > lidocaine
- hypertension
- tachycardia
- hypotension
- prolonged PR interval
- QRS widened
What are the 2 steps of nerve transmission? What does this depend on?
- depolarization - influx of Na ions through large channels
- repolarization - outflux of K ions through channels
impulse transmission depends on gradients
What are the 2 types of nerve fibers that local anesthetics affect?
- small (A delta, B, C) - outermost autonomic and sensory nerve
- larger, myelinated (A gamma, beta, alpha) - motor fibers
sensory blocked before motor!
How does the affect on nerves differ in the different types of local anesthetics?
selectively block sensory vs. motor function - Bupivacaine, Ropivacaine
relatively non-specific - Lidocaine
What are 9 agents used in local and regional blocks?
- local anesthetics - Lidocaine, Bupivacaine, Ropivacaine
- saline
- bicarbonate
- epinephrine
- NSAIDs
- steroids
- alpha agonists
- ketamine
- narcotics
What is the onset and duration of Lidocaine like? What causes toxicity?
10-15 mins, lasts 60-120 mins
IV uptake —> dependent on cardiac, CNS, and hepatic function
What is the onset and duration of Bupivacaine like? What are 2 major differences compared to Lidocaine?
20-30 mins, lasts 4-6 hrs
- selective sensory blockade - motor sparing!
- very cardiotoxic with IV uptake
What are 4 major reasons to add slaine to local anesthetics?
- decreases pain of administration
- helps with spread and increases chance of nerve contact in blind techniques without increasing dose
- decreases chance of toxicity
- increases chances of full coverage, especially for plexus, facial, or compartmental blocks
What are 3 problems with adding epinephrine to local anesthetics?
- vasoconstriction can be detrimental - careful with peripheral digital blocks and in skin flaps!
- acidic - slows onset
- uptake near vascular bed can cause cardiac dysrhythmias and respiratory issues
In what 2 ways does bicarbonate hasten the onset of a blockade? When is it particularly used?
- raises pH, promoting a more permeable form of anesthetic
- improves intracellular binding of the drug
most important in acidic environments, like abscesses and infections
How does the location of surgery, diameter of nerve, and doses of drugs affect dosing of local anesthetics?
further caudal and distal in the animal = less total volume needed
smaller nerve = lower volume needed
higher dose = more analgesia, but more side effects
(opioid = urinary retention!)
How are sites prepared for performing locoregional blocks?
- surgical clip wide with a 40 blade
- clean scrub followed by surgical scrub
- sterile gloves, one hand = very sterile
- have vials, syringes, and needles prepared
How can intraneural injection of epidurals be avoided?
if there is pressure on injection, you are in the nerve —> pull back
What are 2 major reasons to use a reduced volume of local anesthetics in epidurals?
- decreases possibility of toxicity
- decreases chance of intraneural injection
How are nerve stimulators used?
- locator finds the nerve or plexus
- local blockade is delivered
- catheter is introduced to allow continued blockade
How is echolocation used to find nerves and plexi? How can it be used to avoid vascular injections? What limitation is associated?
high-frequency transducers of ultrasounds are used to locate the nerve based on sound waves
color doppler and compound imaging
beam penetration is limited to 5-7 cm
How are locoregional block needles placed? What should be done in blocks near the chest?
- short, deep angle bevel to reduce nerve puncture
- slow and steady advancement
attach syringe to the needle to create a closed system - brachial plexus, thoracic paravertebral
What are 3 purposes to utilize facial and dental blocks?
- reduce pain during and after dental procedures, oral and facial surgeries, and nasal desensitization during rhinoscopy or nasal biopsy
- reduce MAC
- relieve chronic pain
What nerve is responsible for sensory innervation for dental procedures? What are the 4 most common blockades?
trigeminal nerve (CN V) - ophthalmic, maxillary, and mandibular divisions
- maxillary
- mandibular
- infraorbital
- mental