LOCAL ANESTHETICS

Question 1

PROCAINE

Answer 1

ESTER LA
SLOW ONSET, SHORT DOA , NV, HYPERSENSITIVITY 
ONSET: SLOW PKA: 8.9
DURATION: SLOW
LS: 1
PB: 5
DOSE: 7MG/KG

Question 2

TETRACAINE

Answer 2

ESTER LA
SLOW ONSET, LONG DOA, PROFOUND MOTOR BLOCK, SPINAL AND CORNEAL ANESTHESIA, CAUDA EQUINA SYN
ONSET: SLOW PKA: 8.7
DURATION: LONG
LS: 80
PB: 85
DOSE: 3MG/KG, SPINAL - MAX 10MG

Question 3

BUPIVICAINE

Answer 3

AMIDE LA
MOD ONSET, LONG DOA, DIFFRENTIAL NERVE BLOCK, HIGH PB, GOOD FOR ESPIDURAL, SPINAL, PNB, CV TOXIC
ONSET: MODERATE PKA: 8.1
DURATION: LONG 
LS: 30
PB: 95
DOSE: 2.5MG/KG 
SPINAL: (0.75%) 15-20 MG

Question 4

LIDOCAINE

Answer 4

AMIDE LA
RAPID ONSET, 2 ACTIVE METABOLITES, CAUDA EQUINA SYNDROME
ONSET: RAPID PKA 7.9
DURATION: MODERATE 
LS: 4
PB: 65
DOSE: ACLS: 1MG/KG
4MG/KG, 7MG/KG*

Question 5

ETIDOCAINE

Answer 5

AMIDE LA 
RAPID ONSET, LONG ACTING, CV TOXIC
ONSET: RAPID PKA:7.7
DURATION: LONG
LS: 140
PB: 95
DOSE: 4MG/KG, 7MG/KG*
SPINAL: 30-100 MG

Question 6

MEPIVICAINE

Answer 6

AMIDE LA
RAPID ONSET, LONG DOA, E1/2T: 2 HRS, CNS TOXIC, 
ONSET: RAPID PKA: 7.9
DURATION: LONG
LS: 1
PB: 75
DOSE: SPINAL 40-80 MG

Question 7

CHLOROPROCAINE

Answer 7

ESTER LA
FAST ONSET, SHORT DOA, RAPID METABOLISM, OB
ONSET: FAST PKA: 8.7
DURATION: SHORT 
LS: 1
PB: 7 
DOSE: 12MG/KG