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Pharmacology Orals > Exact Classes of Drugs > Flashcards

Exact Classes of Drugs Flashcards

1
Q

Trimethphan

A

Peripheral vasodilator and ganglionic blocker

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2
Q

Sodium Nitroprusside

A

Direct peripheral arterial vasodilator

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3
Q

Nitroglycerine

A

Organic nitrate vasodilator

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4
Q

HYDRALAZINE

A

VASODILATOR

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5
Q

MILRINONE

A

BYPYRIDINE INOTROPIC VASODILATOR WITH PHOPHODIESTERASE INHIB ACTIVITY

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6
Q

CLONIDINE

A

ALPHA 2 ADRENERGIC AGONIST VASODILATOR

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7
Q

KETAMINE

A

NON BARBITUATE INDUCTION, LIKE PCP

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8
Q

ETOMIDATE

A

NON BARBITUATE INDUCTION (IMIDAZOLE DERIVATIVE)

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9
Q

PROPOFOL

A

2, 6 DI ISO PROPOPHENYL; NON BARB INDUCTION

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10
Q

PRECEDEX

A

SELECTIVE ALPHA 2 AGONIST

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11
Q

KETEROLAC

A

NSAID

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12
Q

ESMOLOL

A

SELECTIVE BETA 1 ANTAGONIST

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13
Q

METOPROLOL

A

SELECTIVE BETA 1 ANTAGONIST

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14
Q

LABETOLOL

A

NON SELECTIVE BETA AND ALPHA 1 ANTAGONIST

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15
Q

PROPANOLOL

A

NON SELECTIVE BETA ANTAGONIST BETA 1 & 2

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16
Q

Prazosin

A

alpha 1 adrenergic antagonist

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17
Q

PHENOXYBENZAMINE

A

NON SELECTIVE ALPHA ADRENERGIC ANTAGONIST

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18
Q

PHENTOLAMINE

A

NON SELECTIVE ALPHA ADRENERGIC ANTAGONIST

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19
Q

HYDROCORTISONE

A

CORTICOSTEROID

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20
Q

METHYLPREDNISOLONE

A

CORTICOSTEROID

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21
Q

DEXAMETHASONE

A

CORTICOSTEROID

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22
Q

AMPICILLIN

A

ANTIMICROBIAL, BETA LACTUM, 2ND GEN. PCN, BROAD SPECTRUM, (GI/GU/DENTAL)

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23
Q

CEFAZOLIN

A

ANTIMICROBIAL, BETA LACTUM, 1ST GENERATION, BROAD SPECTRUM

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24
Q

GENTAMYCIN

A

ANTIMICROBIAL, AMINOGLYCOSIDE, BROAD SPECTRUM

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25
Q

CLINDAMYCIN

A

ANTIMICROBIAL, LINCOSAMIDE, NARROW SPECTRUM, TREAT PCN RESIST STAPH AND BACTEROIDES

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26
Q

VANCOMYCIN

A

ANTIMICROBIAL, GLYCOPEPTIDES, BROAD SPECTRUM

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27
Q

METRONIDAZOLE

A

ANTIMICROBIAL, ANTI PROTOAZAN, ANAEROBIC

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28
Q

CIPROFLOXACIN

A

ANTIMICROBIAL, FLUORO QUINOLONE, BROAD SPECTRUM

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29
Q

DANTROLENE

A

DIRECT, CENTRALLY ACTING MUSCLE RELAXANT (TX: MH AND SKELETAL MUSCLE SPASTICITY)

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30
Q

REGLAN

A

ANTI NAUSEA/ANTI EMETIC, DOPAmine ANTAGONIST

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31
Q

DROPERIDOL

A

ANTI NAUSEA/ANTI EMETIC, DOPAmine ANTAGONIST

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32
Q

ONDASETRON/ZOFRAN

A

ANTI NAUSEA/ANT EMETIC, 5HT-3 INHIBITOR SERATONIN ANTAGONIST

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33
Q

PROMETHAZINE/PHENERGAN

A

ANTI NAUSEA/ANTI EMTIC, H1 ANTAGONIST PHENOTHIAZINE

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34
Q

OMEPRAZOLE/PRILOSEC

A

ANTI NAUSEA/ ANTI EMETIC, SUBSTITUTED BENZIMIDAZOLE (PPI)

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35
Q

SODIUM CITRATE BICTIRA

A

ANTI NAUSEA/ ANTI EMETIC, NON PARTICULATE ANTACID

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36
Q

ATROPINE

A

ANTICHOLINERGIC, TERTIARY AMINE, CROSSES BBB

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37
Q

GLYCOPYROLATE

A

ANTICHOLINERGIC, SYNTHETIC QUARTENARY AMMONIUM, DOES NOT CROSS BBB

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38
Q

SCOPALAMINE

A

ANTICHOLINERGIC, TERTIARY AMINE, CROSSES BBB AND PLACENTA

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39
Q

PYRIDOSTIGMINE

A

ANTICHOLINESTERASE INHIBITOR, QUARTENARY AMMONIUM, DOES NOT CROSS BBB

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40
Q

EDROPHONIUM

A

ANTICHOLINESTERASE INHIBITOR, QUARTENARY AMMONIUM, DOES NOT CROSS BBB

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41
Q

NEOSTIGMINE

A

ANTICHOLINESTERASES INHIBITOR, QUARTENARY AMMONIUM, DOES NOT CROSS BBB

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42
Q

PHYSOSTIGMINE

A

ANTICHOLINESTERASE, TERTIARY AMINE, CROSSES BBB, (TX: ATROPINE TOX, MG, GLAUCOMA)

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43
Q

EPINEPHRINE

A

ENDOGENOUS CATECHOLAMINE, NONSELECTIVE ADRENERGIV AGONIST

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44
Q

NOREPINEPHRINE (LEVOPHED)

A

DIRECT ACTING ENDOGENOUS CATECHOLAMINE AND ADRENERGIC AGONIST

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45
Q

DOPAMINE

A

ENDOGENOUS CATECHOLAMINE SYMPATHETIC AMINE ADN ADRENERGIV AGONIST

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46
Q

DOBUTAMINE

A

SYMPATHOMIMETIC, SYNTHETIC CATECHOLAMINE, B1 SELECTIVE AGONIST

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47
Q

VASOPRESSIN

A

EXOGENOUS ANTIDIURETIC PEPTIDE AND VASOPRESSOR

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48
Q

ISOPRETERONOL

A

SYNTHETIC CATECHOLAMINE, B1 >B2, MINIMAL ALPHA

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49
Q

EPHEDRINE

A

SYNTHETIC NON-CATECHOLAMINE, DIRECT AND INDIRECT ADRENERGIC AGONIST

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50
Q

PHENLYEPHRINE

A

SYNTHETIC NON CATECHOLAMINE DIRECT AND INDIRECT ACTING, SELECTIVE ALPHA 1

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51
Q

PHENYTOIN

A

ANTICONVULSANT, ANTIARRHYTHMIC CLASS 1B

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52
Q

PHENOBARBITOL

A

OXYBARBITUATE USED AS AN ANTICONVULSANT

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53
Q

TPL (THIOBARBITUATE)

A

BARBITUATE

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54
Q

METHOHEXITOL (OXYBARBITUATE)

A

BARBITUATE

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55
Q

CIMETIDINE

A

H2 BLOCKER

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56
Q

FAMOTIDINE

A

H2 BLOCKER

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57
Q

RANITIDINE

A

H2 BLOCKER

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58
Q

BENADRYL

A

H1 ANTAGONIST, 1ST GENERATION, CROSSES BBB

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59
Q

HEPARIN

A

ANTICOAGULANT, DVT PROPHYLAXIS, PE tx,

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60
Q

PROTAMINE

A

HEPARIN ANTIDOTE, LMW PROTEIN DERIVED FROM SALMON SEAMEN

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61
Q

INSULIN

A

PANCREATIC HORMONE STRUCTURALLY IDENTICAL TO ENDOGENOUS INSULIN

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62
Q

GLUCAGON

A

SYNTHETIC ANALOG OF ENDOGENOUS GLUCAGON, SECRETED IN RESPONSE TO HYPOGLYCEMIA, USED FOR SPHINCTER OF ODDI SPASM AND BB OD

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63
Q

OCTREOTIDE

A

SOMOSTATIN ANALOG, INHIBITS PRODUCTION AND RELEASE OF INSULIN AND GLUCAGON

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64
Q

OXYTOCIN

A

ENDOGENOUS POST PIT HORMONE

65
Q

RAPID ACTING INSULIN CLASS NAMES

A

LISOPRO (HUMALOG)
ASPART (NOVALOG)
GLULISINE (APIDRA)

66
Q

RAPID ACTING INSULIN MOA

A

MONOMORPH FORM - IMMEDIATELY AVAILABLE - MIMICS REGULAR MEAL RELEASE

67
Q

SHORT ACTING INSULIN CLASS NAMES

A

REGULAR (HUMULIN R, NOVOLIN R)

68
Q

SHORT ACTING INSULIN MOA

A

HEXOMER FORM, TAKES TIME TO BREAK DOWN TO MONOMORPH FORM

69
Q

INTERMEDIATE ACTING INSULIN CLASS NAMES

A

NPH (HUMULIN N, NOVOLIN N)

70
Q

INTERMEDIATE ACTING INSULIN MOA

A

N= NEUTRAL, P=PROTAMINE OFTEN COMBINED IWTH REGULAR INSULIN OR RAPID ACTING INSULIN

71
Q

LONG ACTING INSULIN CLASS NAMES

A

GLARGINE (LANTUS)
DETEMIR (LEVEMIR)
ULTRALENTE

72
Q

LONG ACTING INSULIN MOA

A

VERY PHYSIOLOGIC - NO PEAK, MIMICS BASAL INSULIN SECREITON CAN GIVE RAPID ACTING TO COVER EACH MEAL

73
Q

GLULISINE (APIDRA)

A

RAPID ACTING INSULIN

74
Q

ASPART (NOVALOG)

A

RAPID ACTING INSULIN

75
Q

LISOPRO (HUMALOG)

A

RAPID ACTING INSULIN

76
Q

GLARGINE (LANTUS)

A

LONG ACTING INSULIN

77
Q

DETEMIR (LEVEMIR)

A

LONG ACTING INSULIN

78
Q

ULTRALENTE

A

LONG ACTING INSULIN

79
Q

NPH (HUMULIN N, NOVOLIN N)

A

INTERMEDIATE ACTING INSULIN

80
Q

REGULAR (HUMULIN R, NOVOLIN R)

A

SHORT ACTING INSULIN

81
Q

TOLBUTAMIDE/ CHLOROPROPAMIDE

A

ORAL ANTIDIABETIC MED, SULFONYLUREA 1ST GENERATION

82
Q

GLIPIZIDE (GLUCATROL)
GLYBURIDE (DIABETA)
GLIMEPIRIDE

A

ORAL ANTIDIABETIC MED, SULFONYLUREA 2ND GENERATION

83
Q

CHOLORPROPAMIDE

A

ORAL ANTIDIABETIC MED, SULFONYLUREA 1ST GENERATION

84
Q

GLYBURIDE

A

ORAL ANTIDIABETIC MED, SULFONYLUREA 2ND GEN

85
Q

GLIMEPIRIDE

A

ORAL ANTIDIABETIC MED, SULFONYLUREA 2ND GEN

86
Q

METFORMIN (GLUCOPHAGE)

A

ORAL ANTIDIABETIC MED, BIGUANIDES

87
Q

PIOGLITAZONE (ACTOS)

ROSIGLITAZONE (AVANDIA)

A

ORAL ANTIDIABETIC MEDS , THIAZOLIDINEDIONES (TZDs)

88
Q

ACARBOSE (PRECOSE)

MIGLITOL (GLYSET)

A

ORAL ANTIDIABETIC MED, ALPHA GLUCOSIDASE INHIB

89
Q

ROSIGLITAZONE (AVANDIA)

A

ORAL ANTIDIABETIC MED, TZD

90
Q

ACARBOSE (PRECOSE)

A

ORAL ANTIDIABETIC MED, ALPHA GLUCOSIDASE INHIB

91
Q

MIGLITOL (GLYSET)

A

ORAL ANTIDIABETIC MED, ALPHA GLUCOSIDASE INHIB

92
Q

REPAGLINIDIE (PRANDIN)

A

ORAL ANTIDIABETIC MED, MEGLITINIDES

93
Q

NATEGLINIDE (STARLIX)

A

ORAL ANTIDIABETIC MED, MEGLITINIDES

94
Q

SITAGLIPTAN (JANUVIA)

A

ORAL ANTIDIABETIC MED, GLP-1 MIMETIC AND AGONIST

95
Q

EXENATIDE (BYETTA)

A

ORAL ANTIDIABETIC MED, GLP-1 MIMETIC AND AGONIST

96
Q

ORAL ANTIDIABETIC MED, meGLITINIDES

A

repaGLINIDE (PRANDIN)

nateGLINIDE (STARLIX)

97
Q

oral antidiabetic med, GLP-1 MIMETIC and AGONIST

A

sitagliptan (januvia)

exenatide (byetta)

98
Q

Morphine

A

OPIOID, natural opioid agonst

99
Q

MEPERIDINE

A

OPIOID, PHENYL PIPERIDINE SYNTHETIC OPIOID AGONIST

100
Q

FENTANYL

A

OPIOID, PHENYL PIPERIDINE SYNTHETIC OPIOID AGONIST

101
Q

SUFENTANYL

A

OPIOID, PHENYL PIPERIDINE SYNTHETIC OPIOID AGONIST

102
Q

ALFENTANYL

A

OPIOID, TETRAZOLE FENTANYL DERIVATIVE, SYNTHETIC OPIOID AGONIST

103
Q

REMIFENTANYL

A

OPIOID, PHENYL PIPERDINE SYNTHETIC OPIOID AGONIST WITH ESTER LINK

104
Q

Succhinylcholine

A

DEPOLARIZING NEUROMUSCULAR BLOCKER

105
Q

ATRACURIUM (TRACURIUM)

A

NEUROMUSCULAR BLOCKER, INTERMEDIATE ACTING BISQUATERNARY BENZYLISOQUINOLINE

106
Q

CISATRACURIUM (NIMBEX)

A

NEUROMUSCULAR BLOCKER, INTERMEDIATE ACTING BENZYLISOQUINOLINE STEREOISOMER OF ATRICURIUM

107
Q

ROCURONIUM (ZEMURON)

A

NEUROMUSCULAR BLOCKER, SHORT-INTERMEDIATE ACTING STERIOD TYPE

108
Q

VECURONIUM (NORCURON)

A

NEUROMUSCULAR BLOCKER, INTERMEDIATE ACTING STEROID TYPE MONOQUATERNARY AMINOSTERIOD

109
Q

PANCURONIUM (PAVULON)

A

NEUROMUSCULAR BLOCKER, LONG ACTING STERIOD TYPE BISQUATERNARY AMINOSTEROID

110
Q

MIVACURIUM (MIVACRON)

A

NEUROMUSCULAR BLOCKER, SHORT ACTING BENZYLISOQUINOLINE

111
Q

D-TUBOCURARINE (CURARE)

A

NEUROMUSCULAR BLOCKER, LONG ACTING BENZYLISOQUINOLINE

112
Q

DOXACURIUM (NEUROMAX)

A

LONG ACTING BENZYLISOQUINILINE

113
Q

PIPERCURONIUM (ARDUAN)

A

LONG ACTING STEROID TYPE

114
Q

NALBUPHINE

A

OPIOID AGONIST-ANTAGONIST (MU ANTAGONIST AND FULL OR PARTIAL AGONIST AT KAPPA)

115
Q

BUTORPHANOL

A

OPIOID AGONIST - ANTAGONIST (NASAL SPRAY FOR MIGRANES)

116
Q

DIAZEPAM (VALIUM)

A

BENZODIAZEPINE

117
Q

MIDAZOLAM (VERSED)

A

BENZODIAZEPINE WITH AN IMIDAZOLE RING

118
Q

LORAZEPAM (ATIVAN)

A

BENZODIAZEPINE

119
Q

FLUMAZENIL

A

BENZO RECEPTOR ANTAGONIST, IMIDAZOBENZODIAZEPINE DERIVATIVE

120
Q

NITROUS

A

INHALATION AGENT, INORGANIC, COLORLESS, SWEET GAS AT ROOM TEMP,
MAC: 105
BG: 0.47
VP: 38770

121
Q

HALOTHANE

A

INHALATION AGENT; HALOGENATED ALKALINE DERIVATIVE WITH BROMIDE SUBSTITUTION (SWEET, PUNGENT, CONTAINS THYMOL)
MAC: 0.74
BG: 2.4
VP: 244

122
Q

ENFLURANE

A

INHALATION AGENT, HALOGENATED METHYL ETHYL ETHER (MILD, SWEET, ISOMER OF ISO)
MAC: 1.7
BG: 1.8
VPP: 175

123
Q

ISOFLURANE

A

INHALATION AGENT, HALOGENATED METHYL ETHYL ETHER (ISOMER OF ENFLURANE, PUNGENT)
MAC: 1.15
BG: 1.4
VP: 240

124
Q

DESFLURANE

A

INHALATION AGENT, FLUORINATED METHYL ETHYL ETHER (SIMILAR STRUCTURE TO ISO, PUNGENT, TEC 6, FAST ON/OFF)
MAC: 6
BG: 0.42
VP: 669

125
Q

SEVOFLURANE

A

INHALATION AGENT, FLUORINATED METHYL ISOPROPYL ETHER (IDEAL FOR PEDS, NON PUNGENT, SWEET, EXPENSIVE)
MAC: 2.05
BG: 0.69
VP: 157

126
Q

PROCAINE

A 
LOCAL ANESTHETIC: ESTER 
PKA: 8.9, LS: 1, PB: 5 
DOSE: 7MG/KG
SPINAL: 100-200MG DOA: ~60MIN
PNB: 100-400MG DOA~30 MINUTES
127
Q

AMIODARONE

A

ANTI-ARRHYTHMIC, CLASS 3, ALSO HAS CLASS 1,2,4 PROPERITES

128
Q

ADENOSINE

A

ANTI-ARRHYTHMIC, ENDOGENOUS NUCLEOTIDE

129
Q

DIGOXIN

A

ANTI-ARRHYTHMIC, CARDIAC GLYCOSIDE, MANDAGE AFIB/AFLUTTER

130
Q

QUINIDINE

A

ANTI-ARRHYTMIC, CLASS 1, MANAGE SVT/AFIB

131
Q

PROCAINAMIDE

A

ANTI-ARRYTHMIC, CLASS 1A, ANALOGUE OF PROCAINE (TX: AFIB/VTACH)

132
Q

DILTIZEM

A

CALCIUM CHANNEL BLOCKER CLASS 4 ANTI-ARRHYTHMIC, NON DIHYDROPYRIDINE

133
Q

VERAPAMIL

A

CALCIUM CHANNEL BLOCKER, CLASS 4 ANTI-ARRHYTHMIC, NON DIHYDROPYRIDINE

134
Q

NIFEDIPINE

A

CALCIUM CHANNEL BLOCKER, CLASS 4 ANTI-ARRHYTHMIC, DIHYDROPYRIDINE

135
Q

PROTON PUMP INHIBITORS (-PRAZOLE)

A 
LANSOPRAZOLE
PANTOPRAZOLE
ESOMEPRAZOLE
OMEPRAZOLE
RABEPRAZOLE
136
Q

DICYCLOMINE

A

ANTICHOLINERGIC

137
Q

ANATACIDS

ALUM, CALCIUM, MAG, SODIUM)

A

ALUMINUM HYDROXIDE
MAGNESIUM HYDROXIDE
SODIUM BICARBONATE
CALCIUM CARBONATE

138
Q

MISOPROSTOL

A

PROSTAGLANDIN

139
Q

SODIUM CITRATE

A

ANTACID (NON PARTICULATE ANTACID THERAPY)

140
Q

CISAPRIDE

DOPERIDONE

A

PROKINETIC

141
Q

SEROTONIN

A

5HT pro kinetic drug

142
Q

5ht3 antagonists - prokinetic (-setron)

A

ondasetron
granisetron
dolasetron
tropisetron

143
Q

DEXAMETHASONE

144
Q

FUROSEMIDE

A

LOOP DIURETIC

145
Q

HYDROCHLOROTHIAZIDE

A

THIAZIDE DIURETIC

146
Q

MANNITOL (6 CARBON HEXOSE SUGAR)

A

OSMOTIC DIURETIC

147
Q

ALBUTEROL

A 
RESPIRATORY AGENT, B2 AGONIST SHORT ACTING, 
2 ISOMERS (R & S)
148
Q

TERBUTALINE

A

RESPIRATORY AGENT, BE AGONIST, SHORT ACTING

149
Q

IPRATROPIUM

A

RESPIRATORY AGENT, ANTICHOLINERGIC, QUATERNARY AMINE, SALT DERIVATIVE OF ATROPINE

150
Q

TETRACAINE

A

LOCAL ANESTHETIC: ESTER.
PKA 8.5, LS: 80, PB: 85%
DOSE: 3MG/KG
SPINAL (0.23-1.0%): 5-20 MG DOA~90-200MIN

151
Q

BUPIVICAINE

A

LOCAL ANESTHETIC: AMIDE
PKA 8.1, LS: 30, PB 90%
DOSE 2.5MG/KG
EPIDURAL (0.25-0.75%): 40-225MG DOA~ 180-350MIN
SPINAL (0.5-0.75%: 15-20MG DOA~90-200 MIN
PNB (0.25-0.5%) MAJOR: 225MG MAX.
MINOR: 12.5-100 MG DOA~240-420MIN

152
Q

LIDOCAINE

A 
LOCAL ANESTHETIC: AMIDE 
PKA, 7.9, LS: 4, PB: 65%
DOSE 4MG/KG, 7MG/KG*
ACLS: 1MG/KG
EPIDURAL (1-2%) 150-500MG 
SPINAL (1.5, 5.0%) 30-100MG DOA~60 MIN
PNB: MAJOR (1-2%)500MG MAX. MINOR(1%)50-200 MG
DOA~60MINUTES
153
Q

MEPIVICAINE

A 
LOCAL ANESTHETIC: AMIDE
PKA. 7.6, LS: 1, PB: 75%
DOSE: 
EPIDURAL (1-2%) 150-500MG DOA~120 MIN
SPINAL (4%) 40-80 MG DOA~60 MIN
PNB: MAJOR (1-1.5%) 500MG MAX. MINOR (1%) 50-200MG DOA~180 MINUTES
154
Q

ETIDOCAINE

A

LOCAL ANESTHETIC: AMIDE
PKA 7.7, LS: 140 PB: 95%
DOSE: 4MG/KG, 7MG/KG*

155
Q

CHLOROPROCAINE

A 
LOCAL ANESTHETIC: ESTER
PKA: 8.7, LS: 1, PB: 7%
DOSE 12MG/KG
EPIDURAL (2-3%) 300-900 DOA~60 MIN
PNB: MINOR (2%) 100-400MG DOA~30 MINUTES
156
Q

COCAINE

A

LOCAL ANESTHETIC: ESTER. MET IN LIVER.

DOSE: 3MG/KG

157
Q

LEVOBUPIVICAINE

A 
LOCAL ANESTHETIC: ESTER. 
DOSE:
EPIDRUAL (0.25-0.75%) 40-250MG DOA~240 min
spinal (0.5-0.75%) 15-20MG DOA~120 min
PNB: MAJOR (0.25-0.5%) 225MG MAX.
158
Q

ROPIVACAINE

A 
LOCAL ANESTHETIC: AMIDE
DOSE
EPIDURAL (0.25-0.7%) 40-250MG DOA~240 MIN
SPINAL (0.5-0.75%) 15-20MG DOA~120 MIN 
PNB MAJOR (0.2-0.5%) 250MG MAX. 
MINOR (0.2-0.5%) 10-100MG DOA~240 MIN
159
Q

PRILOCAINE

A 
LOCAL ANESTHETIC: AMIDE 
DOSE
EPIDURAL (1-3%) 150-600MG
PNB MAJOR(1-2%) 600MG DOA ~ 240 MIN
MINOR (1%) 50-200MG DOA~120 MIN

Pharmacology Orals (10 decks)

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