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Pharmacology Orals > Doses > Flashcards

Doses Flashcards

1
Q

Propofol (2,6 di iso prophenol, non barbituate induction)

A

NV: 10mg
Induction: 1-2.5 mg/kg
GA: 100-300 mcg/kg/min
Sedation: 25 mcg/kg/min

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2
Q

Etomidate (non barbituate induction)

A

Induction: 0.3 mg/kg
Maintenance: 10 mcg/kg/min

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3
Q

Ketamine (non barbituate induction agent, like pcp)

A

Induction: .5-2mg/kg
Maintenance: 1-2 mg/kg/hr
Sedation 0.2-0.5 mg/kg IV
>2 mg/kg = delirium

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4
Q

Precedex (selective alpha 2 agonist) (inhibits NE release)

A

1 mcg/kg bolus over 10-15 minutes

0.2-1 mch/kg/hr infusion

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5
Q

Reglan (Dopamine antagonist - similar to procainamide

Anti nausea/ anti emetic

A

10 mg IV over 3-5 minutes; 15-30 minutes before induction

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6
Q

Droperidol (Dopamine antagonist)

anti nausea anti emetic

A

0.625 - 1.25 mg iv

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7
Q

Ondansetron (Zofran)
5 HT3 INHIBITOR SERATONIN ANTAGONIST
anti nausea anti emetic

A

4-8 MG IV

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8
Q

Promethazine (Phenergan)

anti nausea anti emetic

A

7-25 mg IV

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9
Q

Omeprazole (Prilosec)

anti nausea anti emetic

A

20mg PO

40 mg IV

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10
Q 
SODIUM CITRATE (BICITRA)
NON PARTICULATE CLEARN ANTIACID
A

15-30 mL PO 15-30 minutes preop

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11
Q

Hydromorphine

opioid - NO HISTAMINE response

A

0.5-2 MG IV q4-6h

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12
Q

Morphine (natural opioid agonist)

OPIOID

A

2.5-15 mg IV pre/post op

delayed respiratory depression esp with epidural and spinals

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13
Q

Meperedine (Demerol) opioid
phenyl-piperdine synthetic opioid agonist
ob - post op
NO HISTAMINE RELEASE
decrease shivering (kappa and alpha 2)
atropine like structure/ similar to lidocaine

A

50-150 mg IM
5 mg q5min IV
12.5 mg IV shivering

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14
Q

Fentanyl (opioid)
phenyl piperdine synthetic opioid agonist
blunts DVL, spinal and epidural

A

pre-med: 25-100 mcg
analgesia: 1-2 mcg/kg
Intra-op dose: 12.5-100 mcg

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15
Q

Sufentanyl (opioid)
pheyl piperdine synthetic opioid agonist
good in CARDIAC surgery

A

0.1-1 mcg/kg bolus
1-2 mcg/kg minor
2-8 mcv/kg moderate
8-50 mch/kg sole anesthetic

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16
Q

alfentanyl - opioid

Tetrazole fentanyl derivative synthetic opioid agonist, dvl returobulb block, decreas mac,

A

10-20 mch/kg

infusion: 0.25-0.75 mcg/kg/min

17
Q

Remifentanyl (opioid)
phenyl-piperdine synthetic opioid agonist with ester link
good for neuro and outpatient ob

A

0.5-1 mcg/kg over 60 seconds

18
Q

Atropine (anticholinergic)

Tertiary amine - crosses BBB

A

0.01 mg/kg for reversal (edrophonium)
0.4-1 mg bradycardia
1 mg q3-5 minutes for Asystole, PEA

19
Q

Glycopyrolate (anticholinergic)
Synthetic quartenary ammonium
does NOT cross bbb

A
  1. 01-0.02 mg/kg IV (with neostigmine)

0. 1-0.2 mg (anti-sialogogue and bradycardia)

20
Q

Scopalamine (anticholinergic)

tertiary amine - crosses BBB and placenta

A

0.3-0.6 mg IV q4-6h

21
Q

pyridostimine (anticholinesterases)
competitive acetylcholinesterase inhibitor
quartenary ammonium - does NOT cross BBB

A

0.2 mg/kg with glyco 0.01mg/kg - oral for MG

22
Q

edrophonium (anticholinesterases)
comp acetylcholinesterase inhibitor
quart ammonium does NOT cross bbb

A

0.5-1 MG/KG WITH ATROPINE 0.01 MG/KG

23
Q

NEOstigmine anticholinesterase
comp actelycholinesterase inhibitor
quartenary ammonium - does NOT cross bbb

A

0.05-0.07 MG/KG with glyco 0.01 mg/kg

24
Q

physostigmine - anticholinesterase
tertiary amine - cross BBB
for atropine tox., MG, gLAUCOMA

A

15-60 MCG/KG iv q1-2 hours

25
Q

ampicillin - antimicrobial

bETA LACTUM, 2ND GENERATION PCN, BROAD SPECTRUM, GI/GU/DENTAL

A

2 gram IV q 30 minutes

26
Q

Cefazolin - antimicrobial - cephalosporin

beta lactum, 1st generation PCN, broad spectrum,

A

1-2 g iv 30 MINUTES PREOP

27
Q

GENTAMYCIN - ANTIMICROBIAL

Aminoglycoside, broad spectrum

A

60-120 mg iv

TOXIC >9 mcg/ml

28
Q

CLINDAMYCIN - ANTIMICROBIAL
LINCOSAMIDE - SEMI SYNTHETIC - NARROW SPECTRUM
TX PCN RESISTANT STAPH AND BACTEROIDES

A

600 MG IV preop

29
Q

VANCOMYCIN - ANTIMICROBIAL
GLYCOPEPTIDE
BROAD SPECTRUM

A

1 G IN 250 ML

10-15 MG/KG

30
Q

METRONIDAZOLE (FLAYGL) ANTIMICROBIAL

SYNETHIC ANTI BACTERIAL AGENT ANTI PROTOZOAN,

A

500 MG IV OVER 10 - 20 MINUTES PREOP

31
Q

CIPROFLOXACIN - ANTIMICROBIAL

FLUORO QUINOLONE, BROAD SPECTRUM

A

200-400 MG IV OVER 60 MINUTES

32
Q

DANTROLENE

DIRECT , CENTRALL ACTING MUSCLE RELAXANT USED TO TREAT AND PREVENT MH AND MUSCLE SPASITICY

A

2.5 MG/KG IV FOLLOWED BY MAINTENANCE DOSE 2MG/KG IV Q5MINUTES TO TOTAL 10 MG/KG
PO: 4-8 MG.KG/DAY IN 2 DIVIDED DOSES FOR 3 DAYS

Pharmacology Orals (10 decks)

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