Local Anesthetic APEX (Pharm 2) Flashcards
1
Q
A
2
Q
A type nerve fibers
-Alpha, beta, gamma, delta
B type nerve fibers
C type nerve fibers
subtypes?
Velocity?
Function??
A
3
Q
A type fibers:
Alpha
Beta
Gamma
Delta
Functions of each?
A
3
Q
A
4
Q
B nerve fibers?
A
5
Q
C nerve fibers??
SNS:
Dorsal:
A
6
Q
A
7
Q
A
8
Q
A
9
Q
A
10
Q
A
11
Q
A
12
Q
A
13
Q
A
14
Q
A
15
Q
A
Aka:
ionized fraction
Conjugate acid
Protonated species
Cation
16
Q
A
17
Q
A
Amide has -NH
18
Q
A
19
Q
A
20
Q
A
21
Q
A
22
Q
A
23
Q
A
24
25
26
27
28
29
30
31
32
33
Effectis of lido toxicity according to plasma []:
>25
15-25
10-15
5-10
1-5
34
34
35
36
37
Lipid emulsion dose treatment for LAST:
Under 70kg
Over 70kg
38
39
40
41
42
43
44
45
46
MAX dose for EMLA cream??
0-3 months or <5kg
3-12 months or >5kg
1-6 yo and >10 kg
7-12 yo and >20kg
47
48
49
50
51
Ester = no NH in chemical structure
Amide = has NH in chemical structure
52
53
pKa of:
Bup:
Levobup:
Rop:
Lido:
Prilocaine:
Mepivacaine:
Procaine:
Chloroprocaine:
Tetracaine:
54
Effect for LA:
Epi:
Decadron:
Dextran:
Clonidine:
Epi:
Opioid:
Na+ bicarbonate:
Hyaluronic Acid:
