Liver structure and Function Flashcards
name the 2 major lobes of the liver
left and right
name the two minor lobes of the liver
caudate and quadrate
what does the porta provide entry and exit for?
> blood vessels
lymphatic vessels
ducts
nerves
what two ducts form the common bile duct?
common hepatic and cystic duct
what is the bare area of the liver surrounded by?
the coronary ligament
what is the portal triad?
> hepatic portal vein
hepatic portal artery
hepatic duct
what does blood from the alimentary canal drain into?
hepatic portal vein
what does the hepatic portal vein join with to form hepatic sinusoids which create the hepatic vein?
the hepatic artery
what is the function of hepatocytes?
> bile synthesis
nutrient storage
nutrient interconversion
detoxification
what bile pigment is extracted from blood by hepatocytes?
bilirubin
what bile is yellow?
bilirubin
what sort of bile pigments is excreted in yellow urine?
reabsorbed bilirubin
how is bilirubin modified by bacterial enzymes excreted?
in brown faeces
what are bile acids synthesised from?
cholesterol
how are bile acids turned into bile salts?
they are conjugated with glycine/tourine before secretion
how are secreted bile salts recycled?
via the enterohepatic circulation
what are the three layers in the wall of the gallbladder?
> mucosa
muscularis
serosa
what does the sphincter of oddi control?
release of bile and pancreatic juice into the duodenum
what is the effect of fats in the duodenum on the sphincter of oddi and gall bladder?
the release of cck causes the sphincter of oddi to relax and the gall bladder to contract
what is the effect of secretin released by duodenum due to influx of acid (summary)?
> decrease in gastric acid secretion
decrease in gastric emptying
increase in duodenal bicarbonate secretion
increase in pancreatic bicarbonate secretion
increase in bile duct bicarbonate
what is the effect of cck released due to fat in the duodenum?
> decreased gastric emptying
increased enzyme secretion
gall bladder contraction
relaxation of the sphincter of oddi