Liver histology

Question 1

In embryology where does the liver develop from?

Answer 1

Glandular outgrowth of the primitive gut

Question 2

How do absorbed food products pass from the gut to the liver?

Answer 2

Via the hepatic portal vein

Question 3

What are Sinusoids?

Answer 3

wWde vascular channels that separate the plates of hepatocytes

Question 4

What are Kupffer cells and where are they located?

Answer 4

Macrophage type cells scattered around the endothelial cells lining the sinusoids

Question 5

What produces bile and to where is it secreted?

Answer 5

Produced by hepatocytes

Secreted into bile canaliculi, small bile duct, common bile duct then deuodenum

Question 6

What are Portal tracts?

Answer 6

Islands of connective tissue containing branches of the portal vein and hepatic artery that bring blood to the sinusoids. Also has bile ducts which bring bowel to the small gut

Question 7

What privides the sinusoids with blood?

Answer 7

Portal tracts

Question 8

Where does the blood from the portal vein drain into?

Answer 8

Hepatic vein then inferior vena cava

Question 9

Name 2 things transported in the portal tracts

Answer 9

Blood and bile

Question 10

Where in the liver will you find the hepatuc hepatic acinus?

Answer 10

on a portal tract between 2 or more terminal hepatic venules

Question 11

Describe the differences between the zones of the hepatic acinus

Answer 11

Zone 1 is closest to portal tract and receives the most oxygenated blood while zone 3 is furthest away, receiving the least amount of oxygenated blood.