Liver Function Tests Flashcards

1
Q

What is the immediate precursor of bilirubin formation?

A

Biliverdin

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2
Q

In the Evelyn - Malloy method, bilirubin is:

A

Azobilirubin is the pink or purple compound formed

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3
Q

The total bilirubin component of serum consists of direct and indirect bilirubin. What is the best description for direct bilirubin?

A

Water soluble

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4
Q

If the total bilirubin is 4.3 mg/dL and conjugated bilirubin is 2.1 mg/dl, what is the unconjugated bilirubin?

A

2.2 mg/dL

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5
Q

Coupling promoters that maybe used for bilirubin determination

A

Methyl alcohol and caffeine sodium

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6
Q

Dubbin-Johnson syndrome is characterized by?

A

Inability to excrete conjugated bilirubin

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7
Q

The complex that is formed after bilirubin couples with diazotized sulfanilic acid is:

A

Azobilirubin

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8
Q

It is considered as obstructive bilirubin if:

A

There is obstruction of the biliary ract

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9
Q

disease states is conjugated bilirubin a major serum component?

A

Biliary obstruction

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10
Q

Kernicterus is the abnormal accumulation of bilirubin in which tissue?

A

Brain tissue

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11
Q

When the RBS outlives its 120 lifespan, it disintegrates, hemoglobin is released and converted to bile pigments primarily by the?

A

Spleen

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12
Q

Which of the following is the correct SI unit and conversion factor for bilirubin ?

A

Mol/L = 17.1

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13
Q

One of the following is not a cause of unconjugated hyperbilirubinemia.

A

Constricted bile ducts

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14
Q

If the cause of the unconjugated hyperbilirubinemia is the absence of the enzyme conjugating system, UDPGT, the condition is known as:

A

Criglerr-Najjaf syndrome

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15
Q

The greatest activities of serum AST and ALT are seen in which condition

A

Acute hepatitis

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