LIVER FUNCTION TEST Flashcards
- The chief metabolic organ
- A large organ divided unequally into two lobes by a falciform ligament
Liver
- functional unit of the liver.
- Responsible for its metabolic and excretory function.
Lobules
2 major cell types:
o Hepatocytes
o Kupffer cells
also known as the “hepatic macrophage”. Act as
phagocytes that lines the sinusoids of liver.
Kupffer cells
(80%), composed the majority of cells. Performs the major function of liver and its regenerative properties.
Hepatocytes
2 blood supply:
o Hepatic artery
o Portal vein
percentage of hepatic artery blood supply?
(25%)
percentage of Portal vein blood supply?
(75%)
amount of blood that goes in the liver
1500 mL of blood per minute
synthesize substance specifically proteins EXCEPT immunoglobulins
Synthetic function
for the metabolism of bilirubin
Conjugation function
protects the body from potential toxic substances absorbed by the intestine
Detoxification and drug metabolism
this includes bile elimination (including cholesterol and bile salts)
Excretory and Secretory function
acts as storage for fat soluble vitamins (A,D, E, K), some water soluble vitamins and glycogen
Storage function
T/F. TESTS FOR LIVER SYNTHETIC FUNCTION, Quantitates the severity of hepatic dysfunction.
True
