Liver Flashcards
Liver function
Metabolism - material absorbed from GIT
- storage of glycogen
- release of glucose (glucagon from pancreas effects to do so via turning glycogen into glucose in liver)
Protein synth
Inactivation of hormones/drugs
Excretes waste and produces bile
Produced blood clotting factors ( so need to know related diseases as surgery or extraction in the mouth need to know consequences to these on blood clotting)
Liver structure
4 lobes - right (and right lobe proper) and left lobe
- caudate lobe
- quadrate lobe
Falciform ligament
Round ligament
Hepatic artery, hepatic portal vein, inferior vena cava
Gall bladder
Common hepatic duct (formed from R and L hepatic ducts)
Cystic duct (joins to ^)
Common bile duct (the two above combined)
Pancreatic duct
Liver process of producing bile
Biliary system - hepatocytes ( liver cells ) produce bile, stored and conc. in gall bladder
Bile contents
Bile salts - lipid emulsifiers
Waste products ie. bile pigments (bilirubin)
Hepatic portal vein function
Drains unpaired abdominal organs - almost all GIT material absorbed into and passed through liver being processed
How liver functions
Blood from hepatic artery and portal vein flow past hepatocytes in large capillaries (sinusoids - low pressure vascular channels)
Sinusoids drain to the hepatic veins and then inferior vena cava
Bile flows in opposite direction
Sinusoids structure
Hepatic lobule - portal triad, portal vein in centre, hepatocytes arranged in linear cords between capillary network alongside bile canaliculus tubes collecting bile released from hepatocytes
Liver issues
Hepatomegaly Cirrhosis Viral hepatitis Obstructive jaundice Hepatic carcinoma