Liver Flashcards

1
Q

How many lobes is the liver divided into?

A

3 (Right, Left, Caudate)

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2
Q

How many segments is the liver divided into?

A

8 ( 9 including caudate segment)

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3
Q

How many segments does the caudate lobe have?

A

1

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4
Q

How many segments does the left lobe have?

A

4

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5
Q

How many segments does the right lobe have?

A

4

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6
Q

What is the difference between hepatic veins and portal veins in appearance?

A

hepatic veins do not have echogenic walls

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7
Q

What vessels consist in the portal triad?

A

Main Portal vein, Hepatic Artery, CHD

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8
Q

What is the portal triad covered by?

A

Glissons Capsule

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9
Q

What is the purpose of the main lobar fissure?

A

Divides right and left hepatic lobes by an oblique plane between the inferior vena cava and gallbladder fossa

Also divides anterior segment of right lobe from medial segment of left lobe

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10
Q

What does the Right hepatic vein divide?

A

Anterior and posterior segments

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11
Q

What does the Left hepatic vein divide?

A

Medial and Lateral segments

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12
Q

What is the Ligament Venosum?

A

Remnant of ductus venosus

Separates the left lobe from the caudate lobe

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13
Q

Explain fetal circulation?

A

Umbilical Vein (Ligamentum Teres) > Left portal vein > Ductus venosus ( Ligamentum venosum) > IVC

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14
Q

What is Hepatopetal flow?

A

Flow toward the liver

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15
Q

What is hepatofugal flow?

A

Flow away from liver

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16
Q

What is upper limits for portal vein diameter?

A

13 mm

Large diameter suggests portal hypertension

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17
Q

What type of flow does hepatic veins have?

A

Hepatofugal

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18
Q

What type of flow do portal veins have?

A

Hepatopetal

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19
Q

What is Parvus Tardus?

A

proximal anastomotic stenosis

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20
Q

What recanalizes in case of liver cirrhosis?

A

Ligamentum Teres

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21
Q

What is the Falciform Ligament?

A

peritoneal reflection or fold created by the passage of the embryonic umbilical vein from the umbilicus to the left branch of portal vein

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22
Q

What is the Coronary ligament?

A

Suspend liver from the diaphragm.

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23
Q

Right and left triangular ligament?

A

Reflections of right and left bare area

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24
Q

What is considered Hepatomegaly?

A

Greater than 15.5 cm superior- inferior dimension

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25
Q

What is a Reidels Lobe?

A

Inferior projection of the right lobe

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26
Q

What are hepatic granulomas?

A

Small calcifications of macrophages seen in liver and spleen

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27
Q

What is hepatitis?

A

Liver inflammation resulting from infectious or noninfectious agents

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28
Q

What labs might be elevated in hepatitis?

A

ALT
AST
Conjugated and unconjugated Bilirubin

29
Q

What might be seen with acute hepatitis?

A

“starry night” (periportal cuffing)
hypoechoic liver parenchyma
liver enlargement
hyperechoic portal vein walls

30
Q

What is the most common source for pyogenic (bacterial) abscess?

A

Biliary Tract Disease

31
Q

What is an amebic abscess?

A

Parasite from the intestines, reaches liver via portal vein.

32
Q

What is a fungal abscess (Candidiasis)?

A

A fungal infection of the blood that results in small abscesses in the liver.
“Wheel within Wheel”
“ Bull’s eye”

33
Q

What is echonicoccal cyst (Hydatid disease)?

A

Tapeworms

34
Q

What is Schistosomiasis?

A

Most common parasitic infections in humans

Major cause of portal hypertension worldwide

35
Q

What is focal fatty infiltration?

A

focal regions of increased echogenicity within normal liver parenchyma. Most commonly occurs at the porta hepatis

36
Q

What is focal fatty sparring?

A

focal regions of normal liver parenchyma within a fatty infiltrated liver. Occurs adjacent to GB, in porta hepatis, in caudate lobe and at the liver margins

37
Q

What is Glycogen Storage Disease? (Von Gierke disease)

A

Genetically acquired disorder that results in excess deposition of glycogen in the liver.
Absence or deficiency of one of the enzymes responsible for making or breaking down glycogen

38
Q

What is cirrhosis?

A

diffuse process of fibrosis and distortion of normal liver architecture

39
Q

What is the main cause of cirrhosis?

A

Alcohol abuse

40
Q

What is portal hypertension?

A

increased pressure in the portal venous system. Normal pressure is 5 to 10 mmHg. When pressure gradient increases, considered portal hypertension

41
Q

What is the major cause of portal hypertension?

A

Cirrhosis

42
Q

What are the four types of portal hypertension?

A
  1. Extrahepatic presinusoidal: Portal vein thrombus
  2. Intrahepatic presinusoidal: Schistomiasis
  3. Intrahepatic: Cirrhosis
  4. Intrahepatic postsinusoidal: Hepatic vein thrombus
43
Q

How does portal hypertension affect the spleen?

A

Splenomegaly

44
Q

What does TIPS stand for?

A

Transjugular Intrahepatic Portal- systemic Shunt

45
Q

What is the ,point for TIPS?

A

shunts created to lower portal pressure avoiding the development or rupture of gastroesophageal varices and reducing the accumulation of ascites

46
Q

Where is this device places?

A

Between a hepatic vein and a portal vein (usually RHV and RPV)

47
Q

What type of flow should TIPS demonstrate?

A

Hepatofugal

48
Q

What is the criteria for TIPS malfunction?

A
  1. low shunt velocity ( <50 cm/sec)
  2. High focal shunt velocity ( >190 cm/sec)
  3. Hepatopetal LPV or RPV
  4. Hepatofugal MPV
  5. Absent shunt flow
49
Q

What is the only exception for TIPS with a recanalized umbilical vein?

A

The LPV may be in either direction of flow. Hepatopetal or Hepatofugal

50
Q

What is the most common TIPS material used?

A

GORE Viatorr endoprosthesis

51
Q

Explain Portal vein thrombus?

A

Most commonly associated with portal hypertension.

With portal thrombus, extensive collaterals can form at the liver hilum. (“ cavernous transformation of portal vein”)

52
Q

What is Budd-Chiari Syndrome?

A

Hepatic vein obstruction

53
Q

What are patients signs for budd chiari?

A

Ascites, Hepatomegaly, splenomagaly

54
Q

What might you find with Budd-Chiari syndrome?

A

Caudate lobe enlarges with atrophy of the Right and Left lobes. IVC can be compressed with the large caudate lobe

55
Q

What is portal vein gas?

A

Air noted within the intrahepatic portal veins.

56
Q

Explain what a liver cyst is?

A

Fluid filled space lined by biliary epithelium. Usually referred to as nonparasitic simple cysts

57
Q

What are some characteristics of a simple cyst?

A

Anechoic, thin walled, Acoustic Enhancement

58
Q

What are some characteristics of a hemorrhagic cyst?

A

cyst with internal echoes, RUQ pain, decreasing hemotocrit

59
Q

What is a cavernous hemangioma?

A
  • Most common benign liver tumor

- Hyperechoic and posterior enhancement

60
Q

What is Focal Nodular Hyperplasia?

A

benign solid liver mass that is believed to be a developmental hyperplastic lesion instead of a true neoplasm

61
Q

What does a Focal Nodular Mass contain?

A

Hyperplastic hepatocytes in abnormal arrangement with dense fibrous tissue. Contains proliferating bile ducts, Kupffer cells, connective tissue and a central stellate scar

62
Q

What is Focal Nodular Mass known as?

A

“Stealth lesion”

Displaces intrahepatic blood vessels

63
Q

Know about hepatic adenomas?

A
  • associated with oral contraceptives
  • Associated with Glycogen storage disease
  • Patient pain due to tumor hemorrhage
64
Q

Know about hepatic lipoma?

A
  • rare

- tuberous sclerosis and congenital familial disease associated with hepatic lipomas and angiomyolipomas

65
Q

Know about Hepatic Carcinoma

A
  • most common primary malignancy of liver
  • occurs in patients with cirrhosis and chronic liver disease
  • Invades venous structures: Portal veins, Hepatic veins, and IVC
  • Increased AFP, AST, ALT
66
Q

Know about the different types of liver mets

A
  1. Hyperechoic metastasis: GI tract
  2. Hypoechoic Mets: Lymphoma
  3. Bull’s eye or Target Mets: Lung
  4. Calcified Mets: Mucinous Adenocarcinoma of colon
  5. Cystic Mets: Leiomyosarcoma
67
Q

What is a Hepatoblastoma?

A

uncommon malignant liver neoplasm occurring in infants and children

  • increased AFP levels
  • associated lung mets and portal vein invasion
68
Q

Review Labs

A

Page 36 in ESP

69
Q

Tumor Markers

A

Page 38 in ESP