Liver Flashcards
What can acetoaminophen toxicity cause?
acute liver failure
What kind of bilirubin, unconjugated or conjugated, is there is pre hepatic jaundice?
Unconjugated
What type of jaundice can pregnancy or bile duct loss cause?
intra hepatic
What type of jaundice can tumours in the head of the pancreas cause?
post hepatic
What type of liver disease is micronodular?
alcoholic
Is cirrhosis reversible?
No
What does cirrhosis appear like on histology?
bands of fibrosis separating regenerative nodules of hepatocytes
What do the whiteish splodges on histology in alcoholic fatty liver disease show?
steatosis
Is there a carrier state in Hep A?
No
What does interface hepatitis show on histology?
piecemeal necrosis
What type of inheritance is there is in all 3 of haemochromatosis, A1AT deficiency and Wilson’s?
autosomal recessive
In Wilson’s where does copper accumulate?
liver and brain
What are levels of caeruloplasmin like in Wilson’s?
low
In what condition is there cytoplasmic globules of unsecreted globules of protein in liver cells?
Alpha-1 AT deficiency
What type of carcinoma in the liver is associated with HBV and HCV?
hepatocellular carcinoma
