(Lipshutz) Acquired Neuromuscular Weakness and Early Mobilization in the Intensive Care Unit

Question 1

Prolonged immobility and bedrest lead to catabolism and muscle atrophy, and are associated with _______ and ________

Answer 1

Critical illness neuromyopathy and ICU-acquired weakness

Question 2

Implementation of early mobilisation therapy requires changes in ICU culture, including

Answer 2

Decreased sedation and bedrest

Question 3

Critical Illness Neuromyopathy is an umbrella term for a spectrum of neuromuscular disorders associated with critical illness, including

Answer 3

Critical illness polyneuropathy (CIP) and critical illness myopathy (CIM)

Question 4

Nutrition plays a role in CINM (critical illness neuromyopathy) as its been found _______ _______ and _________ play a role

Answer 4

Protein-energy malnutrition, electrocorticosteroids and glutamine deficiency

Question 5

Lipshutz concluded early mobilisation is a

Answer 5

Safe and feasible intervention for many critically ill patients, and is associated with improved outcomes.

Question 6

Neuromuscular weakness in the ICU is common; approximately 50% of ICU patients with ____, ______, or ___________ have electrophysiologic evidence of neuromuscular dysfunction

Answer 6

Sepsis, multi organ failure or prolonged mechanical ventilation

Question 7

ICU-acquired weakness is defined as

Answer 7

bilateral symmetrical limb weakness, is the clinical manifestation of CINM

Question 8

ICU-acquired weakness is associated with

Answer 8

Respiratory muscle weakness, difficulty weaning from the ventilator and prolonged ICU length of stay