Lipoproteins

Question 1

orlistat

Answer 1

decreased absorption of triglycerides

Question 2

phosphatidic acid phosphatase

Answer 2

decreased triglyceride synthesis

Question 3

ileum resection

Answer 3

decreased enterohepatic circulation of bile salts

Question 4

Function of ApoB100

Answer 4

used for interacting the with LDL receptor

Question 5

LDL receptor does what…

Answer 5

receptor mediated endocytosis of LDL

Question 6

LDL receptor does what…

Answer 6

receptor mediated endocytosis of LDL

Question 7

Statins exert their effect on? And what happens?

Answer 7

HMG-CoA Reductase. This inhibits the rate-limiting step in cholesterol biosynthesis.

Question 8

Statins exert their effect on? And what happens?

Answer 8

HMG-CoA Reductase. This inhibits the rate-limiting step in cholesterol biosynthesis.

Question 9

What is responsible for transporting energy to most of the cells of the body?

Answer 9

chylomicrons, VLDL, and non-esterified fatty acid

• NOT HDL or LDL
• non-esterified = free fatty acids

Question 10

What is responsible for transporting energy to most of the cells of the body?

Answer 10

chylomicrons, VLDL, and non-esterified fatty acid

• NOT HDL or LDL
• non-esterified = free fatty acids

Question 11

A patient with hypertiglyceridemia would most likely benefit from a low card diet if which lipoprotein is elevated in blood levels?

Answer 11

VLDL

Question 12

What are phytosterols and what do they do?

Answer 12

Plant stanols and sterols are a group of naturally occurring compounds (called phytosterols) found in plant cell membranes. Because they are structurally similar to cholesterol, when consumed, they compete with cholesterol for absorption in the digestive system. As a result, cholesterol absorption is blocked, and blood cholesterol levels go down.