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Gastrointestinal & Nutrition > Gastrointestinal Secretions > Flashcards

Gastrointestinal Secretions Flashcards

1
Q

Source of Gastrin

A

G Cells of stomach, antrum, duodenum

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2
Q

Source of Somatostatin

A

D Cells of pancreatic islets and GI mucosa

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3
Q

Source of CCK

A

I Cells of duodenum and jejunum

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4
Q

Source of Secretin

A

S cells of duodenum

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5
Q

Source of GIP

A

K Cells of duodenum and jejunum

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6
Q

Source of Motilin

A

small intestine

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7
Q

Source of VIP

A

parasympathetic ganglia in sphincters, gallbladder, and small intestine

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8
Q

Source of Intrinsic Factor

A

parietal cells of stomach

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9
Q

Source of Gastric Acid

A

parietal cells of stomach

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10
Q

Source of Pepsin

A

chief cells of stomach

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11
Q

Source of Bicarbonate

A

mucosal cells of stomach and Brunner glands of duodenum

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12
Q

Stimulus and Action and Inhibition of Gastrin

A

Stimulus: protein, distention, vagus nerve (via GRP)

Action: stimulates gastric acid secretion, mucosal growth

Inhibition: acid and somatostatin

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13
Q

Stimulus and Action and Inhibition of Somatostatin

A

Stimulus: acid

Action: Inhibits release of all GI hormones. Inhibits Gastrin secretion – 2 pathways (direct & indirect)!!

Inhibition: Vagal stimulation

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14
Q

Stimulus and Action and Inhibition of CCK

A

Stimulus: small peptides, amino acids, fat

Action: Stimulates pancreatic enzyme secretion, pancreatic bicarb secretion, gallbladder contraction, growth of exocrine pancreas. Inhibits gastric emptying.

Inhibition: N/A?

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15
Q

Stimulus and Action and Inhibition of Secretin

A

Stimulus: Acid, fat, CCK

Action: Stimulates Pepsin secretion, pancreatic bicarb secretion, biliary bicarb secretion, growth of exocrine pancreas. Inhibits Gastric Acid secretion.

Inhibition: N/A?

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16
Q

Stimulus and Action and Inhibition of GIP

A

Stimulus: Protein, fat, carb

Action: Stimulates insulin release. Inhibits Gastric Acid secretion.

Inhibition: N/A?

17
Q

Stimulus and Action and Inhibition of Motilin

A

Stimulus: Fat, acid, nerve

Action: Stimulates gastric motility and intestinal motility.

Inhibition: N/A?

18
Q

Stimulus and Action and Inhibition of VIP

A

Stimulus: Enteric plexus???

Action: Relaxes GI smooth muscle including the LES. Stimulates pancreatic bicarb secretion. Inhibits gastric acid secretion.

Inhibition: N/A?

*(Homologous to Secretin)

19
Q

Stimulus and Action and Inhibition of Nitric Oxide

A

Stimulus:

Action:

Inhibition:

20
Q

Stimulus and Action and Inhibition of Pepsin

A

Stimulus:

Action:

Inhibition:

Gastrointestinal & Nutrition (9 decks)

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