Lipoproteins

Question 1

Lipoprotein

Answer 1

Transport molecules for tags and cholesterol in the body

Question 2

Structure of lipoproteins

Answer 2

Thin monolayer of phospholipids with a hydrophobic center containing cholesterol esters/tags. Apoproteins are on the outer layer to allow for binding to different receptors

Question 3

What is cholesterol made from

Answer 3

Acetal coa

Question 4

What metabolic pathway is cholesterol synthesis. What is the main regulatory step of this synthesis

Answer 4

This is an anabolic state that requires lots of energy and it is mainly regulated by HMG -COA reductase

Question 5

What is the difference between cholesterol and cholesterol esters

Answer 5

Cholesterol esters are e more hydrophobic because the -OH group is replaced by an acyl group by acyl transferase

Question 6

What leads to high cholesterol

Answer 6

Dysfunction with receptors that recycle lipoproteins, excess fat synthesis, or issues with HMG -COA reductase activity

Question 7

How can you differentiate between lipoproteins

Answer 7

By apoproteins,tag and cholesterol percentage

Question 8

Chylomicron

Answer 8

Largest lipoprotein made in small intestine and contains apoprotein 48

Question 9

Very low density lipoprotein (VLDL)

Answer 9

Lipoprotein that goes into the circulatory system

Question 10

Explain how VLDL gets converted to LDL

Answer 10

Lipoprotein lipase hydrolyses tags in VLDL creating intermediate density lipoprotein and then low density lipoprotein

Question 11

What are the good and bad cholesterol

Answer 11

Bad cholesterol: low density lipoprotein
Good cholesterol: high density lipoprotein- transports cholesterol back to liver for recycling and tells body when there is enough cholesterol present

Question 12

Fill in the blank.
The _______________monitors cholesterol levels in the body

Answer 12

Liver