Lipoproteins Flashcards
Function of lipoproteins?
transport cholesterol in the blood
What is the arrangement of lipoproteins making them useful for cholesterol transport?
outer-glycoproteins
inner-lipid
What are the 4 types of glycoproteins?
HDL (high density lipid)
LDL (low density lipid)
VLDL (very low density lipid)
IDL (intermediate density lipid)
HDL where are they formed? are they good or bad? protein:lipid ratio? function?
Formed in the Liver
good, empty cholesterol
highest protein:lipid ratio
Remove cholesterol from blood and cells
Where is the cholesterol then taken?
taken to the liver which secreted it into bile or converted into bile salts
LDL where are they formed? are they good or bad? protein:lipid ratio? function?
formed in the plasma
bad
low protein:lipid ratio
deposit cholesterol in cells
VLDL
synthesised in?
function?
hepatocytes
carries triglycerides from glucose in liver to adipocytes
IDL
function?
Are VLDL intermediates, converted to LDL
When is beta oxidation of fatty acids increased?
in fasted (post absorptive state)
increased glucagon
decreased insulin
what are the 3 types of beta oxidation?
peroxisomal
mitochondrial (in imms)
CYP4a in ER