Lipid Transport And Insulin

Question 1

What happens in the absorptive state to lipid?

From blood flow to ….

Answer 1

Inflow to liver from portal system

Question 2

What happens to lipid after it gets to the liver in absorptive state?

Answer 2

Packed and sent to adipocytes in LDL

Question 3

Absorptive

What is found on the adipocytes surface and what does it do to the lipid?

Answer 3

Lipoprotein lipase (LPL) and releases free fatty acids

Question 4

Absorptive

What happens to the free fatty acids in the adipocytes?

Answer 4

Reform triglycerides in adipocytes

Question 5

Post absorptive
The demand for what increases?
What happens at the adipocytes?

Answer 5

Demand for energy increases

TGs release FFA into blood under hormone sensitive lipase action

Question 6

post absorptive

What does hepatic lipase do?

Answer 6

Allows uptake Of FFA into liver for beta oxidation

Question 7

What does insulin do?

Answer 7

Promotes storage of triglycerides in adipocytes

Question 8

What happens in insulin resistance in regards to FA and glucose?

Answer 8

Increased FFA and glucose in blood
Less use of FA as immediate fuel, more glucose
More fatty deposits and less efficient energy produced