Lipids 3 Flashcards
1
Q
How are fatty acids synthesised?
A
From acetyl CoA, derived from excess protein and carbohydrates
2
Q
Where does fatty acid synthesis occur?
A
In the cytosol
3
Q
Acetyl CoA is formed in the mitochondria - how is it transferred to the cytosol?
A
The citrate shuttle
4
Q
What are steroid hormones?
A
Chemical messengers in the body e.g. glucocorticoids
5
Q
What is cholesterol?
A
A starting material for synthesis of steroid hormones
6
Q
What are eicosanoids?
A
Signalling molecules denied from omegas 3 and 6 fatty acids
7
Q
What are eicosanoids precursors to?
A
Protogladins, thromboxanes and leukotrienes
8
Q
What do eicosanoids regulate?
A
- Inflammatory response
- Pain and fever (prostaglandins)
- Blood pressure (Prostacyclin)
- Blood clotting (thromboxanes)
- Reproductive functions and menstrual cramps
9
Q
What are COX inhibitors?
A
COX complexes are enzyme systems involved in the synthesis of prostaglandins - inhibitors stop these synthetic processes
