Essential Pharmacology

Question 1

Chemical messengers show specificity how?

Answer 1

By only binding to a certain complementary shaped receptor

Question 2

Signal transduction can alter what processes?

Answer 2

1. Membrane permeability
2. Metabolism
3. Secretory activity
4. Rate of cell proliferation/differentiation
5. Contractile activity

Question 3

What two receptor types are involved with signal transduction?

Answer 3

Intracellular and Plasma receptors

Question 4

Describe the action of nitrous oxide and state what kind of receptor it acts upon

Answer 4

Binds to guanylyl cyclase (intracellular receptor) to generate cGMP as a secondary messenger which regulates cell activity

Question 5

Receptors that acts as ion channels are called what?

Answer 5

Ionotropic

Question 6

Give an example of a receptor with intrinsic enzyme activity

Answer 6

Tyrosine kinase (cell differentiation and proliferation)

Question 7

What process are stimulated by receptors that interact with JAK kinases?

Answer 7

Protein synthesis

Question 8

What is the largest family of receptors?

Answer 8

G-protein coupled receptors