Lipids 1 Flashcards

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1
Q

What are lipids?

A
  • Heterogeneous organic molecules

- Insoluble in water

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2
Q

What are some of the functions of lipids?

A
  • Stores of energy
  • Structural elements of membranes
  • Enzyme cofactors
  • Hormone function
  • Vitamins A, D, E, K
  • Signalling molecules
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3
Q

Describe the classification of lipids

A

Fatty acids, triglycerides, phospholipids, glycolipids, steroids

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4
Q

Describe the transition temp of unsaturated fats

A

Low TT - typically found as liquids

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5
Q

Describe the transition temp of saturated fats

A

High TT - typically found as solids

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6
Q

Humans cannot introduce double (C=C) bonds past the ninth carbon of a fatty acid chain - how do we get them? What are they called?

A

Essential fatty acids - ingested

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7
Q

What are the effects of omega-3 fatty acids

A

Lowers plasma cholesterol, prevents atherosclerosis and lowers [triglyceride]

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8
Q

What do omega-6 fatty acids do?

A

The same as omega-3 but less effective

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9
Q

What is the main dietary lipid?

A

TAGs

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10
Q

What is the main site of lipid digestion in the body?

A

Small intestine

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11
Q

Lipid digestion is promoted from what enzymes and aided by what two processes?

A

Pancreatic enzymes (lipases) promoted by emulsification by bile salts and peristalsis (mechanical mixing)

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12
Q

What are bile salts?

A

Biological detergents derived from cholesterol

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13
Q

Products of lips digestion include what?

A

Micelles (spherical lipid droplets in aqueous environments with bile salts)

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14
Q

How are free fatty acids transported in the blood?

A

In a complex with albumin

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15
Q

Chylomicrons are what?

A

Digested fatty acids bound to apoB-48 protein to be transported in the blood

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16
Q

Describe the structure of lipoproteins

A

Hydrophobic core, hydrophilic surface

17
Q

What is steatorrhea?

A

Lipid malabsorption leads to excess lipids in faeces. Recognisable by foul smelling and floating physical waste