Lipids Flashcards

1
Q

It is a family of substances that are insoluble in water, but soluble in nonpolar and low polarity solvents.

A

Lipids

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2
Q

It is generally called “bad cholesterol”

A

(LDL) Low-density Lipoprotein

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3
Q

Why fatty acids are regarded to be amphipathic?

A

It has both polar (hydrophilic head) and nonpolar (hydrophobic tail) groups.

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4
Q

True or False.

Most fatty acids found in nature have an even number of carbon atoms.

A

True (usually 14 to 24)

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5
Q

A type of fatty acid that has one or more carbon-carbon double bonds.

A

Unsaturated fatty acid

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6
Q

A type of fatty acid that consists of carbon-carbon single bonds.

A

Saturated fatty acid

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7
Q

What is the function of unsaturated fatty acids in membranes?

A

They give the fluidity/interior of the membrane (a liquid-like structure)

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8
Q

Fatty acids that must be part of our diets since we cannot synthesize them.

A

Essential fatty acids

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9
Q

It is generally called “good cholesterol”

A

(HDL) High-density Lipoprotein

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10
Q

A type of fatty acid that is solid at room temperature.

A

Saturated fatty acid

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11
Q

A type of fatty acid that is liquid at room temperature.

A

Unsaturated fatty acid

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12
Q

True or False.

Unsaturated fatty acids have higher melting points than saturated fatty acids.

A

False.

Saturated have higher melting points (the greater the degree of unsaturation, the lower the melting point)

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13
Q

What is the backbone of all triglycerides that contain 3 hydroxyl (OH) groups?

A

Glycerol

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14
Q

What is the linkage between three alcohol groups (glycerol) and fatty acids in triacylglycerol?

A

Ester linkages

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15
Q

The main component of animal fats and plant oils that consists of glycerol and 3 fatty acids.

A

Triacylglycerols (Triglycerides)

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16
Q

A type of triglyceride where all three fatty acid groups are the same.

A

Simple triglycerides

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17
Q

A type of triglyceride where two or three fatty acid groups are different.

A

Mixed triglyceride

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18
Q

What is the state of a triglyceride if it contains a high proportion of long-chain saturated fatty acids?

A

Solid (fats)

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19
Q

What is the state of a triglyceride if it contains a high proportion of long-chain unsaturated fatty acids?

A

Liquid (oils)

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20
Q

What affects the structural difference between fats and oils?

A

Degree of unsaturation

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21
Q

The process of converting unsaturated liquid oils to solids through reduction reaction (adding H2)

A

Hydrogenation

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22
Q

A reactant used in a saponification reaction of fats/oil

A

a strong base/lye

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23
Q

What is the source of trans fatty acids?

A

Hydrogenation

24
Q

Why do trans fatty acids are not generally recognized as safe?

A

Diets that contain large amounts of trans fats tend to lead to high levels of serum cholesterol and a higher ratio of LDL to HDL (risk factors for heart disease)

25
Recipe for saponification (making of soap)
1. Acid (fatty acid; oil) | 2. Strong Base (NaOH; lye)
26
A complex lipid that consists of 1 alcohol, 2 fatty acids, and 1 phosphate ester.
Phospholipid
27
What is the alcohol in a glycerophospholipid?
Glycerol
28
If the phospholipid has choline alcohol, what will you call it?
Phosphatidylcholine (lecithin)
29
What alcohols can be found in cephalin?
Ethanolamine or serine
30
What alcohol can be found in phosphatidylinositols?
Inositols
31
Phospholipids that contain sphingosine alcohol.
Sphingolipid
32
Where can we find sphingolipids?
In the myelin sheaths or nerve cell membranes
33
Complex lipids that contain carbohydrates.
Glycolipids
34
A class of glycolipids that contain ceramide
Cerebroside
35
A group of plant and animal lipids that contains a tetracyclic ring structure.
Steroids
36
True or False. | Progesterone serves as the starting compound for both sex hormones and adrenocortical hormones.
True
37
The most abundant steroid in the human body which serves as a component in the plasma membrane.
Cholesterol
38
They are regarded as the "carrier" of cholesterol.
Lipoproteins
39
A lipoprotein that carries triglycerides (fats) synthesized by the liver.
Very-low density lipoprotein
40
True or False. | If LDL receptors are sufficient, cholesterol accumulates in the blood.
False. If LDL receptors are sufficient, they will be able to distribute the cholesterol to different cells. (keeping the cholesterol in the blood at a normal level)
41
What adrenocorticoid hormone regulates the concentration of ions (Na+ and K+)?
Mineralocorticoids
42
What adrenocorticoid hormone controls carbohydrate metabolism?
Glucocorticoid
43
The most important mineralocorticoid that enhances the reabsorption of Na+ and Cl- ions in the kidney tubules (controls tissue swelling).
Aldosterone
44
The major glucocorticoid that increases the glucose and glycogen concentrations in the body.
Cortisol
45
What are the oxidation products of cholesterol?
Bile salts
46
Complete the sentence. | Bile salts are synthesized in the ___ and stored in ___.
Kidney - gallblader
47
What is the purpose of bile salts?
Emulsify dietary fats and aid in their absorption and digestion.
48
What are the precursors of prostaglandins, thromboxane, and leukotrienes?
Arachidonic acids
49
What COX enzyme is responsible for the production of prostaglandins in inflammations causing fever and pain?
COX-2
50
What COX enzyme is responsible for the production of prostaglandins to ensure homeostasis in the body?
COX-1
51
A substance that causes blood clotting and constriction of blood vessels. (encourages platelet aggregation or clumping)
Thromboxanes
52
A substance that acts to mediate hormonal responses.
Leukotrienes
53
What kind of lipoprotein carries cholesterol to the cells/cell membrane?
(LDL) Low-density Lipoprotein
54
A lipoprotein that has the largest percentage of cholesterol and a low percentage of proteins.
(LDL) Low-density Lipoprotein
55
What is the carbon number location of the phosphate group in the glycerophospholipid backbone?
C3