Lipid Catabolism

Question 1

C2

Answer 1

acetic

Question 2

C10

Answer 2

capric

Question 3

C12

Answer 3

lauric

Question 4

C16

Answer 4

palmitic

Question 5

C18

Answer 5

stearic

Question 6

C16:1

Answer 6

palmitoleic

Question 7

C18:1

Answer 7

oleic

Question 8

C18:2

Answer 8

linoleic

Question 9

lipases

Answer 9

triacylglyceride —> FA + Glycerol

Question 10

glycerol kinase

Answer 10

glycerol —> Glycerol 3 P

Question 11

glycerol 3 phosphate dehydrogenase

Answer 11

glycerol 3 P —> dihydroxy acetone P

NAD+ —> NADH + H+

Question 12

fatty acyl CoA synthetase

Answer 12

FA —> FA-CoA

ATP —> AMP + PPi

Question 13

acyl CoA dehydrogenase

Answer 13

FA-CoA —> trans 2 enoyl CoA

FAD —> FADH2

Question 14

enoyl CoA hydratase

Answer 14

trans 2 enoyl CoA —> beta hydroxy acyl CoA

requires water

Question 15

beta hydroxy acyl CoA dehydrogenase

Answer 15

beta hydroxy acyl CoA —> beta ketoacyl CoA

NAD+ —> NADH + H+

Question 16

acyl CoA transferase

Answer 16

beta ketoacyl CoA —> Acyl CoA + AcCoA

requires CoA-SH

Question 17

mono unsaturated FA

Answer 17

requires enoyl CoA isomerase before the enoyl CoA hydratase to make sure the C=C is in the trans configuration
one less FADH2 is produced

Question 18

Odd numbered FA

Answer 18

one less ATP produced

enters TCA cycle as succinyl CoA

Question 19

propionyl CoA carboxylase

Answer 19

propionyl CoA —> D methylmalonyl CoA
ATP —> ADP
requires HCO3-, and biotin

Question 20

methymalonyl CoA epimerase

Answer 20

D conf. —> L conf.

reversible

Question 21

methylmalonyl CoA mutase

Answer 21

L conf. —> succinyl CoA
requires vitamin B 12
reversible