Amino Acid Catabolism

Question 1

amino transferase

transamination

Answer 1

amino acid —> keto acid
A keto glutarate —> glutamate (always involved)
amine is transferred from the AA to the keto acid
requires pyridoxal phopshate
delta G = 0
reversible

Question 2

amino dehydrogenase

deamination

Answer 2

amino acid ---> keto acid
NAD+ ---> NADH + H+
requires water
reversible
generally occurs when NH3 conc. is low

Question 3

amino acid oxidase

deamination

Answer 3

amino acid —> keto acid

O2 + H2O —> H2O2 + free NH3

Question 4

aspartate deaminase

deamination

Answer 4

able to remove the amine without use of a redox reaction

Question 5

serine dehydratase

deamination

Answer 5

able to remove the amine without use of a redox reaction